Finding a novel method to generate a chiral plasmonic material has been highlighted in the last decades for its unique light‐matter interactions. Recently, an aqueous based peptide directed synthesis of chiral plasmonic gold nanoparticle with exceptional chiroptic response has been reported. Especially, the facile and precise control of chirality using biomolecules allows potential expansion of chiral metamaterial synthesis. In this work, we show a significant enhancement of chiroptic response by simultaneous introduction of multiple bio‐molecular chiral modifiers, glutathione and homooligonucleotide containing thymine. Compared to previously synthesized single chiral plasmonic nanoparticles using only glutathione molecules, further addition of an oligonucleotide into the growth solution induces a two‐fold increase of dissymmetric factor. We believe that the presented synthetic method proposes an effective route of chiral metamaterial morphology and property control for versatile applications.

中文翻译：

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谷胱甘肽和聚（T）20核苷酸合成的手性432螺旋II纳米颗粒。

在过去的几十年中，寻找一种新颖的方法来生成手性等离子体材料已因其独特的光-质相互作用而得到了强调。最近，已经报道了具有优异的手性响应的水基肽指导的手性等离激元金纳米粒子的合成。特别地，使用生物分子的手性的容易和精确的控制允许手性超材料合成的潜在扩展。在这项工作中，我们通过同时引入多种生物分子手性修饰剂，谷胱甘肽和含胸腺嘧啶的同聚核苷酸，显示出了对手性反应的显着增强。与以前仅使用谷胱甘肽分子合成的单手性等离子体纳米颗粒相比，将寡核苷酸进一步添加到生长溶液中会导致不对称因子增加两倍。