Freeform Microfluidic Networks Encapsulated in Laser‐Printed 3D Macroscale Glass Objects,Advanced Materials Technologies

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Freeform Microfluidic Networks Encapsulated in Laser‐Printed 3D Macroscale Glass Objects
Advanced Materials Technologies ( IF 6.4 ) Pub Date : 2020-01-13 , DOI: 10.1002/admt.201900989
Zijie Lin _{1,

2} , Jian Xu _{1,

2} , Yunpeng Song _{1,

2} , Xiaolong Li _{1,

2} , Peng Wang ₂ , Wei Chu ₂ , Zhenhua Wang _{1,

2} , Ya Cheng _{1,

2,

3,

4}

Affiliation

Large‐scale microfluidic microsystems with complex 3D configurations are highly in demand by both fundamental research and industrial application, holding the potentials for fostering a wide range of innovative applications such as organ‐on‐a‐chip as well as continuous‐flow manufacturing. However, freeform fabrication of such systems remains challenging for current fabrication techniques in terms of fabrication resolution, flexibility, and achievable footprint size. Herein, ultrashort pulse laser microfabrication of freeform microfluidic circuits with high aspect ratios embedded in 3D printed glass macroscale objects is reported. Centimeter‐length microchannels with uniform diameters are achieved by distributing a string of extra‐access ports along the channels for avoiding the overetching. After the chemical etching, the extra‐access ports are sealed using carbon dioxide laser–induced localized glass melting. A model hand of 3D laser–printed fused silica with a size of ≈3 cm × 2.7 cm × 1.1 cm in which the whole blood vessel system is encapsulated is demonstrated.

中文翻译：

封装在激光打印的3D宏观玻璃物体中的自由形式微流体网络

基础研究和工业应用都对具有复杂3D配置的大规模微流体微系统提出了很高的要求，它们具有促进广泛的创新应用（例如片上器官以及连续流制造）的潜力。然而，就制造分辨率，灵活性和可实现的占地面积而言，这种系统的自由形式制造对于当前的制造技术仍然具有挑战性。本文中，报道了具有高纵横比的自由形式微流体电路的超短脉冲激光微加工嵌入在3D打印的玻璃宏观物体中。通过沿通道分布一串额外的访问端口可避免直径过大的厘米长的微通道，从而避免过度蚀刻。化学蚀刻后额外的入口使用二氧化碳激光诱导的局部玻璃熔化来密封。演示了3D激光打印熔融石英的模型手，其尺寸约为≈3 cm×2.7 cm×1.1 cm，其中封装了整个血管系统。

更新日期：2020-02-10

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