BACKGROUND Highly walkable neighbourhoods may increase transport-related and leisure-time physical activity and thus decrease the risk for obesity and obesity-related diseases, such as type 2 diabetes (T2D). METHODS We investigated the association between walkability and prevalent/incident T2D in a pooled sample from five German cohorts. Three walkability measures were assigned to participant's addresses: number of transit stations, points of interest, and impedance (restrictions to walking due to absence of intersections and physical barriers) within 640 m. We estimated associations between walkability and prevalent/incident T2D with modified Poisson regressions and adjusted for education, sex, age at baseline, and cohort. RESULTS Of the baseline 16,008 participants, 1256 participants had prevalent T2D. Participants free from T2D at baseline were followed over a mean of 9.2 years (SD: 3.5, minimum: 1.6, maximum: 14.8 years). Of these, 1032 participants developed T2D. The three walkability measures were not associated with T2D. The estimates pointed toward a zero effect or were within 7% relative risk increase per 1 standard deviation with 95% confidence intervals including 1. CONCLUSION In the studied German settings, walkability differences might not explain differences in T2D.

中文翻译：

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在德国不同地区的成年人中，步行能力及其与流行和偶发糖尿病的关联：来自五个德国队列的汇总数据结果。

背景技术高度步行的邻里可以增加与交通有关的运动和休闲时间的体育活动，并因此降低患肥胖症和与肥胖有关的疾病（例如2型糖尿病（T2D））的风险。方法我们调查了来自五个德国队列的样本中的步行能力与流行/事件T2D之间的关联。参与者的地址分配了三个步行性度量：公交车站的数量，兴趣点和640 m以内的阻抗（由于没有交叉路口和物理障碍而导致的步行限制）。我们通过修正的Poisson回归估计了步行性和流行/事件T2D之间的关联，并针对教育程度，性别，基线年龄和队列进行了调整。结果在基线1,008名参与者中，有1256名参与者患有流行性T2D。基线时无T2D的参与者平均随访9.2年（SD：3.5，最小：1.6，最大：14.8年）。其中，有1032名参与者开发了T2D。这三个步行性措施与T2D无关。估计结果显示为零效应，或每1标准偏差的相对风险增加7％以内，包括95的置信区间为1。结论在德国研究环境中，步行性差异可能无法解释T2D的差异。