BACKGROUND Dye localization is a useful method for the resection of unidentifiable small pulmonary lesions. This study compares the transbronchial route with augmented fluoroscopic bronchoscopy (AFB) and conventional transthoracic CT-guided methods for preoperative dye localization in thoracoscopic surgery. METHODS Between April 2015 and March 2019, a total of 231 patients with small pulmonary lesions who received preoperative dye localization via AFB or percutaneous CT-guided technique were enrolled in the study. A propensity-matched analysis, incorporating preoperative variables, was used to compare localization and surgical outcomes between the two groups. RESULTS After matching, a total of 90 patients in the AFB group (N = 30) and CT-guided group (N = 60) were selected for analysis. No significant difference was noted in the demographic data between both the groups. Dye localization was successfully performed in 29 patients (96.7%) and 57 patients (95%) with AFB and CT-guided method, respectively. The localization duration (24.1 ± 8.3 vs. 21.4 ± 12.5 min, p = 0.297) and equivalent dose of radiation exposure (3.1 ± 1.5 vs. 2.5 ± 2.0 mSv, p = 0.130) were comparable in both the groups. No major procedure-related complications occurred in either group; however, a higher rate of pneumothorax (0 vs. 16.7%, p = 0.029) and focal intrapulmonary hemorrhage (3.3 vs. 26.7%, p = 0.008) was noted in the CT-guided group. CONCLUSION AFB dye marking is an effective alternative for the preoperative localization of small pulmonary lesions, with a lower risk of procedure-related complications than the conventional CT-guided method.

中文翻译：

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增强荧光支气管镜（AFB）与经皮CT引导下的染料定位在胸腔镜下切除小肺结节：一项倾向匹配研究。

背景技术染料定位是用于切除无法识别的小肺部病变的有用方法。这项研究比较了胸腔镜手术中术前染料定位的经增强支气管镜检查（AFB）和常规经胸CT引导方法的经支气管途径。方法在2015年4月至2019年3月期间，共有231名通过AFB或经皮CT引导技术接受了术前染料定位的小肺部病变患者参加了研究。结合术前变量进行倾向匹配分析，以比较两组之间的定位和手术结果。结果匹配后，AFB组（N = 30）和CT引导组（N = 60）总共选择了90例患者进行分析。两组之间的人口统计学数据均无显着差异。使用AFB和CT引导方法分别成功地对29例患者（96.7％）和57例患者（95％）进行了染料定位。两组的定位时间（24.1±8.3 vs. 21.4±12.5 min，p = 0.297）和等效剂量的放射线照射（3.1±1.5 vs. 2.5±2.0 mSv，p = 0.130）相当。两组均未发生与手术相关的主要并发症。然而，在CT引导下，发现气胸的发生率较高（0 vs. 16.7％，p = 0.029）和局灶性肺内出血（3.3 vs. 26.7％，p = 0.008）。结论AFB染料标记是术前定位小肺部病变的有效替代方法，与常规CT引导方法相比，手术相关并发症的风险较低。