Abstract Surface modification with polymerization films containing amino groups is a reliable way to improve the bioactivity/biocompatibility of implants or build a drugs immobilization/release system on their surface. In this work, APTES films containing amino groups were achieved using a plasma deposition device. The amine density was adjusted by changing the Ar flow and the highest value of 9.03% was achieved at 50 sccm. Such APTES films showed good bone bioactivity as apatite was significantly induced in 14–28 days’ SBF immersion. Furthermore, the plasma deposited APTES films exhibited high hydrophilicity (WCAAPTES ≈ 21°) with good stability resisting water (WCARinse ≈ 30°–38°), low cytotoxicity (cytotoxicity level = 0), and high anti-hemolysis ability (Hemolysis rate = 1.03%). All the results confirmed APTES films fabricated in our plasma system could be widely used in biomedical area.

中文翻译：

---

等离子沉积 APTES：生物医学应用的潜在薄膜

摘要 用含氨基的聚合膜进行表面改性是提高植入物生物活性/生物相容性或在其表面构建药物固定/释放系统的可靠方法。在这项工作中，使用等离子体沉积设备获得了含有氨基的 APTES 薄膜。通过改变 Ar 流量来调整胺密度，在 50 sccm 时达到 9.03% 的最高值。这种 APTES 膜显示出良好的骨生物活性，因为磷灰石在 14-28 天的 SBF 浸泡中被显着诱导。此外，等离子体沉积的 APTES 薄膜表现出高亲水性（WCAAPTES ≈ 21°）、良好的抗水稳定性（WCARinse ≈ 30°–38°）、低细胞毒性（细胞毒性水平 = 0）和高抗溶血能力（溶血率 = 1.03%）。