We put together a special issue on current approaches in systems biology with a focus on mathematical modeling of metabolic networks. Mathematical models have increasingly been used to unravel molecular mechanisms of complex dynamic biological processes. We here provide a short introduction into the topics covered in this special issue, highlighting current developments and challenges.

中文翻译：

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系统生物学：现状和挑战。


我们整理了一份关于系统生物学当前方法的特刊，重点关注代谢网络的数学建模。数学模型越来越多地被用来揭示复杂动态生物过程的分子机制。我们在此对本期特刊所涵盖的主题进行简短介绍，重点介绍当前的发展和挑战。