A combined mechano- and chemo-bactericidal nanomorphology, consisting of periodical surface structures on silicon with deposited nanoparticles of selenium, tellurium oxide, antimony oxide and silver, was fabricated via laser ablation in deionized water with femto- and nanosecond laser systems. The resulting functional surfaces were tested against the formation of Staphylococcus aureus biofilms, and their morphology and elemental composition was characterized with scanning electron microscopy and energy-dispersive x-ray and Raman spectroscopy. Antibacterial properties were suggested to originate from the combined chemical toxicity of nanoparticles and the mechanical damage caused by the sharp nanoscale relief on silicon.

中文翻译：

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细菌变线症：具有嵌入的生物毒性纳米粒子的激光产生的硅纳米剃须刀可防止形成持久的生物膜

在飞秒和纳秒激光系统中，通过在去离子水中进行激光烧蚀，制造了一种组合的机械杀菌和化学杀菌的纳米形态，该形态包括硅上的周期性表面结构以及沉积的硒，碲，氧化锑，氧化锑和银的纳米颗粒。测试所得的功能表面对金黄色葡萄球菌生物膜形成的影响，并通过扫描电子显微镜，能量色散X射线和拉曼光谱对它们的形态和元素组成进行表征。抗菌性能被认为源自纳米颗粒的综合化学毒性和由硅上急剧的纳米级浮雕引起的机械损伤。