INTRODUCTION According to multiple studies, e-cigarette use among adolescents is associated with subsequent smoking initiation. However, little is known about its effect on the transition from smoking initiation to daily smoking. METHODS Using retrospective data from a French national representative survey collected in 2017 (n = 39,115), we analyzed the role of ever using e-cigarettes on daily cigarette smoking status at 17 among ever smokers (n = 21,401). Risk-ratios (RR) were computed through modified Poisson regressions with an inverse probability of treatment weighting (IPTW) approach. RESULTS Among French adolescents aged 17, 16.8 % declared current e-cigarette use (1.9 % reported daily use) and 34.1 % cigarette smoking (25.1 % reported daily smoking). Among ever-smokers, adolescents who declared having ever used e-cigarettes were less likely than those who did not to transition to daily smoking at 17: RR = 0.62 95 %CI [0.60 - 0.64]. We found similar results for those who experimented with e-cigarettes before initiating smoking, RR = 0.76 95 %CI [0.66 - 0.89]. CONCLUSIONS Our results found no evidence of an increased risk of transitioning to daily smoking at 17 among ever-smokers who also experimented with e-cigarettes. Further studies should investigate the longer-term role of vaping on future smoking habits with the use of causal inference methods.

中文翻译：

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电子烟实验是否会增加法国年轻吸烟者向日常吸烟的过渡？

引言根据多项研究，青少年使用电子烟与随后吸烟有关。然而，关于其对从吸烟开始到每天吸烟的过渡的影响知之甚少。方法使用2017年收集的法国国家代表性调查的回顾性数据（n = 39,115），我们分析了曾经使用电子烟对17岁吸烟者（n = 21,401）中每日吸烟状况的影响。风险比（RR）是通过修正的Poisson回归以治疗权重的逆概率（IPTW）方法计算的。结果在17岁的法国青少年中，有16.8％的人宣布当前使用电子烟（举报的每日吸烟率为1.9％）和34.1％的吸烟（举报的每日吸烟率为25.1％）。在烟民中，宣布曾经使用过电子烟的青少年比那些没有在17岁时过渡到日常吸烟的青少年的可能性要低：RR = 0.62 95％CI [0.60-0.64]。对于在开始吸烟之前使用电子烟进行实验的人，我们发现了类似的结果，RR = 0.76 95％CI [0.66- 0.89]。结论我们的研究结果未发现在也尝试过电子烟的经常吸烟者中17岁过渡到日常吸烟的风险增加的证据。进一步的研究应使用因果推断方法调查吸烟对未来吸烟习惯的长期作用。结论我们的研究结果未发现在也尝试过电子烟的经常吸烟者中17岁过渡到日常吸烟的风险增加的证据。进一步的研究应使用因果推断方法调查吸烟对未来吸烟习惯的长期作用。结论我们的研究结果未发现在也尝试过电子烟的经常吸烟者中17岁过渡到日常吸烟的风险增加的证据。进一步的研究应使用因果推断方法调查吸烟对未来吸烟习惯的长期作用。