BACKGROUND Physical multimorbidity, defined as the presence of two or more chronic physical conditions, is widespread and reduces life expectancy and quality of life in older adults. Sedentary behavior (SB) is increasingly identified as a risk factor for a range of chronic physical conditions, independent of physical activity. OBJECTIVES To investigate associations between physical multimorbidity and SB in older adults. STUDY DESIGN We used cross-sectional data from a population-based sample of 6903 adults aged ≥50 years who participated in the Irish Longitudinal Study on Ageing (TILDA) in 2009-2011. We conducted multivariable linear and logistic regression analyses to assess associations between multimorbidity and SB. MAIN OUTCOME MEASURES Self-reported minutes/day of SB and high SB (≥ 8 h/day). RESULTS We found that most of the 14 individual chronic physical conditions included here were associated with greater SB. Those with stroke (OR = 2.63, 95 % CI = 1.69, 4.10) and cirrhosis (OR = 2.53, 95 %CI = 1.19, 5.41) were the most likely to be classified with high SB. Time spent in SB and the prevalence of high SB increased linearly with number of chronic conditions. Multivariable regression models adjusting for sociodemographic and psychological factors, disability, social network, and physical activity showed that, compared with people with none, those with ≥4 chronic physical conditions had 1.45 times greater odds (OR = 1.45, 95 % CI = 1.09, 1.93) of high SB and higher mean minutes/day of SB (β = 21.37, 95 % CI = 5.53, 37.20). CONCLUSIONS Our results suggest that physical multimorbidity is associated with SB and highlight the need for prospective research to examine the directionality and mechanisms of these associations.

中文翻译：

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老年人的身体多病和久坐行为：爱尔兰老龄化纵向研究 (TILDA) 的结果

背景身体多发病，定义为存在两种或两种以上慢性身体状况，是普遍存在的，降低了老年人的预期寿命和生活质量。久坐行为 (SB) 越来越多地被确定为一系列慢性身体状况的危险因素，与身体活动无关。目的 调查老年人身体多发病与 SB 之间的关联。研究设计 我们使用了来自 6903 名 50 岁以上成年人的基于人口样本的横断面数据，这些成年人参加了 2009-2011 年爱尔兰老龄化纵向研究 (TILDA)。我们进行了多变量线性和逻辑回归分析来评估多发病与 SB 之间的关联。主要结局指标自我报告的 SB 分钟数/天和高 SB 分钟数（≥ 8 小时/天）。结果 我们发现，这里包括的 14 种个体慢性身体状况中的大多数都与更大的 SB 相关。中风 (OR = 2.63, 95% CI = 1.69, 4.10) 和肝硬化 (OR = 2.53, 95%CI = 1.19, 5.41) 最有可能被归类为高 SB。在 SB 中花费的时间和高 SB 的患病率随着慢性病的数量线性增加。调整社会人口统计学和心理因素、残疾、社交网络和身体活动的多变量回归模型显示，与没有慢性身体状况的人相比，患有≥4 种慢性身体状况的人的几率高 1.45 倍（OR = 1.45，95 % CI = 1.09， 1.93) 的高 SB 和更高的平均分钟/天 SB (β = 21.37, 95 % CI = 5.53, 37.20)。