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Screening for cognitive impairment in non-affective psychoses: A comparison between the SCIP and the MoCA
Schizophrenia Research ( IF 3.6 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.schres.2020.01.005
Martino Belvederi Murri 1 , Federica Folesani 1 , Silvia Costa 1 , Bruno Biancosino 2 , Cristina Colla 1 , Luigi Zerbinati 1 , Rosangela Caruso 1 , Maria Giulia Nanni 1 , Scot E Purdon 3 , Luigi Grassi 1
Affiliation  

BACKGROUND Neuropsychological performance has a strong impact on real-life functioning and clinical outcomes in psychosis. However, conducting lengthy cognitive assessments may not be feasible in routine clinical practice. Brief, reliable and cost-effective tools are highly needed, but few studies are available to guide clinician choice. METHODS The purpose of this study was to compare the performance of two widely used, short instruments: the Screen for Cognitive Impairment in Psychiatry (SCIP) and the Montreal Cognitive Assessment (MoCA). These instruments were validated in a sample of patients with psychotic disorders and healthy controls, using the Repeatable Battery for the Assessment of Neuropsychological Status (RBANS) and other instruments to assess executive functions, as comparators. RESULTS Patients fared worse than controls across almost all cognitive domains, with effect sizes ranging from 0 (MoCA naming) to 2.08 (SCIP total). Receiver Operator Curve analysis of patient and control performance suggested a better convergent validity for the SCIP (total score AUC: 0.85; 95%CI: 0.79-0.90; Se: 76%, Sp: 83%, PPV: 85%, NPV: 73%) than the MoCA (AUC: 0.78; 95%CI: 0.72-0.85; Se: 69%, Sp: 76%, PPV: 78.7%, NPV 66%). CONCLUSIONS The Screen for Cognitive Impairment in Psychiatry seems to be a more sensitive and specific screening tool than the MoCA to identify cognitive impairment among patients with psychotic disorders.

中文翻译:

筛查非情感性精神病的认知障碍:SCIP 和 MoCA 之间的比较

背景神经心理学表现对精神病的现实生活功能和临床结果有很大影响。然而,在常规临床实践中进行冗长的认知评估可能不可行。非常需要简短、可靠和具有成本效益的工具,但很少有研究可以指导临床医生的选择。方法 本研究的目的是比较两种广泛使用的短工具的性能:精神病学认知障碍筛查 (SCIP) 和蒙特利尔认知评估 (MoCA)。这些工具在精神病患者和健康对照的样本中得到验证,使用可重复评估神经心理状态的电池 (RBANS) 和其他工具来评估执行功能,作为比较器。结果 在几乎所有认知领域,患者的表现都比对照组差,影响范围从 0(MoCA 命名)到 2.08(SCIP 总数)。患者和对照表现的受试者工作曲线分析表明 SCIP 具有更好的收敛效度(总分 AUC:0.85;95%CI:0.79-0.90;Se:76%,Sp:83%,PPV:85%,NPV:73 %) 比 MoCA (AUC: 0.78; 95% CI: 0.72-0.85; Se: 69%, Sp: 76%, PPV: 78.7%, NPV 66%)。结论 精神病学认知障碍筛查似乎是比 MoCA 更敏感和特异性的筛查工具,用于识别精神病患者的认知障碍。患者和对照表现的受试者工作曲线分析表明 SCIP 具有更好的收敛效度(总分 AUC:0.85;95%CI:0.79-0.90;Se:76%,Sp:83%,PPV:85%,NPV:73 %) 比 MoCA (AUC: 0.78; 95% CI: 0.72-0.85; Se: 69%, Sp: 76%, PPV: 78.7%, NPV 66%)。结论 精神病学认知障碍筛查似乎是比 MoCA 更敏感和特异性的筛查工具,用于识别精神病患者的认知障碍。患者和对照表现的接受者操作曲线分析表明 SCIP 具有更好的收敛效度(总分 AUC:0.85;95%CI:0.79-0.90;Se:76%,Sp:83%,PPV:85%,NPV:73 %) 比 MoCA (AUC: 0.78; 95% CI: 0.72-0.85; Se: 69%, Sp: 76%, PPV: 78.7%, NPV 66%)。结论 精神病学认知障碍筛查似乎是比 MoCA 更敏感和特异性的筛查工具,用于识别精神病患者的认知障碍。
更新日期:2020-04-01
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