The QuEChERS (quick, easy, cheap, effective, rugged, and safe) ultrasound-assisted method was successfully used to determine the presence of contaminants of emerging concern (CECs) in both the growing medium (i.e. soil) and vegetable samples (i.e. potato, onion, celery, parsnip and carrot) cultivated in household gardens under field conditions impacted by the application of livestock manure mixed with human waste. CECs with a broad range of physico-chemical properties including pharmaceuticals, plasticizers, herbicides, personal care products, and biocides were investigated. Among all studied CECs, diclofenac (DCL), carbamazepine, bisphenol A (BPA) and estrogenic hormones (estrone (E1), 17α-ethinyl estradiol (EE2)) were detected and quantified in vegetable samples with a concentration range from 0.114 to 13.3 ng/g fresh weight (f.w.), while BPA, E1, and EE2 were detected in soil samples with concentration ranges from 0.526 to 0.830 ng/g f.w., 0.121-0.199 ng/g f.w. and 0.118-0.333 ng/g f.w., respectively. DCL was only quantified above the limit of quantification in one soil sample (0.151 ng/g f.w.). The human health risk was estimated using the threshold of toxicological concern approach and a standard diet for two segments of the population (i.e. adult and child). The consumption of investigated vegetables contaminated with CECs poses no risk for the Serbian population.

中文翻译：

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将人类废物作为肥料用于农业生产中，是否会由于受到关注的污染物而对人类健康产生不利影响？

QuEChERS（快速，简便，便宜，有效，坚固且安全）超声辅助方法已成功用于确定生长介质（即土壤）和蔬菜样品（即马铃薯）中是否存在新出现的污染物（CEC） ，洋葱，芹菜，欧洲防风草和胡萝卜）在田间条件下种植，这些田间条件受到将牲畜粪便与人类废物混合使用的影响。研究了具有广泛理化特性的CEC，包括药物，增塑剂，除草剂，个人护理产品和杀生物剂。在所有研究的CEC中，在蔬菜样品中检测到并定量了双氯芬酸（DCL），卡马西平，双酚A（BPA）和雌激素（雌酮（E1），17α-乙炔雌二醇（EE2）），其浓度范围为0.114至13.3 ng / g新鲜重量（fw），而BPA，在土壤样品中检测到的E1和EE2的浓度范围分别为0.526至0.830 ng / g fw，0.121-0.199 ng / g fw和0.118-0.333 ng / g fw。仅在一种土壤样品中定量的DCL超过定量极限（0.151 ng / g fw）。使用毒理学关注阈值法和针对两部分人群（即成人和儿童）的标准饮食估算了人类健康风险。食用受CEC污染的经过调查的蔬菜不会对塞尔维亚人口造成任何风险。使用毒理学关注阈值法和针对两部分人群（即成人和儿童）的标准饮食估算了人类健康风险。食用受CEC污染的经过调查的蔬菜不会对塞尔维亚人口造成任何风险。使用毒理学关注阈值法和针对两部分人群（即成人和儿童）的标准饮食估算了人类健康风险。食用受CEC污染的经过调查的蔬菜不会对塞尔维亚人口造成任何风险。