A simple molecular phosphorescent Ru(II) probe P1 has been synthesized by the reaction of 5-aldehyde-2,2′-bipyridine with ruthenium(II) chlorides under mild conditions. The probe upon interaction with different cation and anion showed high selectivity and sensitivity for cyanide ion (CN‒) through phosphorescence “turn-on” response in aqueous solution (60% water) with a detection limit of 0.75 μM. The significant phosphorescence enhancement (∼ 30-fold) is attributed to the nucleophilic addition of cyanide ion to the aldehyde groups of the ruthenium complex in 3 : 1 stoichiometry, in which a naked-eye sensitive orange red color of solution changed to a yellow. The generation of cyanohydrin species through nucleophilic addition has been confirmed by 1H NMR, FT-IR and mass spectra. Based on the color change of the solution, a visual colorimetric strip was prepared, which also showed good detection performance on cyanide ion with quick response time. The prominent efficiency of the Ru(II) probe proved the potential possibility of application in biosystems relating with cyanide ion.

通过使5-醛-2,2'-联吡啶与氯化钌（II）在温和的条件下反应，合成了一种简单的分子磷光Ru（II）探针P1。通过与水溶液（60％的水）中的磷光“开启”响应，探针在与不同阳离子和阴离子相互作用时对氰化物离子（CN 3）表现出很高的选择性和灵敏度，检测极限为0.75μM。显着的磷光增强（约30倍）归因于氰化物以3：1的化学计量比向钌络合物的醛基团进行亲核加成，其中肉眼敏感的橙红色溶液变为黄色。通过1 H NMR，FT-IR和质谱证实了通过亲核加成生成氰醇种类。根据溶液的颜色变化，制备了可见的比色条，该条也显示出对氰化物离子的良好检测性能，响应时间短。Ru（II）探针的突出效率证明了在与氰化物离子有关的生物系统中应用的潜在可能性。