The surface morphology of the substrate is one of the decisive factors for ion-desorption efficiency in surface-assisted laser desorption/ionization mass spectrometry (SALDI-MS). Understanding the impacts on the surface morphology of the substrate during laser desorption/ionization is the premise for improving the performance of SALDI-MS. In this study, the correlations of ion-desorption efficiency and internal energy transfer with surface morphology, including the total surface area, optical absorption, and surface voidage, were systematically investigated on the basis of ordered silicon nanopillar arrays (NAPAs). The results suggest that the SALDI-MS substrate has enough optical absorption for effective ion desorption by enhancing internal energy transfer and promoting the restructuring of the silicon surface; the high surface voidage of NAPAs can increase the ion-desorption intensity because it can increase the temperature of the substrate surface. This work reveals that with enough optical absorption, high surface voidage is vital for the design of a SALDI-MS substrate based on silicon.

中文翻译：

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定制硅纳米柱阵列上SALDI-MS中离子解吸的表面形态研究

基材的表面形态是表面辅助激光解吸/电离质谱（SALDI-MS）中离子解吸效率的决定性因素之一。了解激光解吸/电离过程中对基材表面形态的影响是提高SALDI-MS性能的前提。在这项研究中，在有序硅纳米柱阵列（NAPA）的基础上，系统地研究了离子解吸效率和内部能量转移与表面形态（包括总表面积，光吸收和表面空隙）的相关性。结果表明，SALDI-MS衬底具有足够的光吸收能力，可以通过增强内部能量传递和促进硅表面的重构来实现有效的离子解吸；NAPA的高表面空隙率可以提高离子解吸强度，因为它可以提高基材表面的温度。这项工作表明，具有足够的光吸收能力，高空隙率对于基于硅的SALDI-MS基板的设计至关重要。