Various biofunctional hydrogel materials can be fabricated in aqueous media through the self-assembly of peptide derivatives, forming supramolecular nanostructures and their three-dimensional networks. In this study, we describe the self-assembly of new Fmoc-dipeptides comprising α-methyl-L-phenylalanine. We found that the position and number of methyl groups introduced onto the α carbons of the Fmoc-dipeptides by α-methyl-L-phenylalanine have a marked influence on the morphology of the supramolecular nanostructure as well as the hydrogel (network) formation ability. This article describes the self-assembly of Fmoc-dipeptides comprising α-methyl-L-phenylalanine. The position and number of methyl groups introduced onto the α carbons of the Fmoc-dipeptides as α-methyl-L-phenylalanine have a marked influence on the morphology of supramolecular nanostructures and the hydrogel formation ability.

中文翻译：

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包含α-甲基-L-苯丙氨酸的Fmoc-二肽的自组装和水凝胶形成能力

通过肽衍生物的自组装，可以在水性介质中制造各种生物功能水凝胶材料，形成超分子纳米结构及其三维网络。在这项研究中，我们描述了包含 α-甲基-L-苯丙氨酸的新 Fmoc-二肽的自组装。我们发现α-甲基-L-苯丙氨酸在Fmoc-二肽的α碳上引入甲基的位置和数量对超分子纳米结构的形态以及水凝胶（网络）形成能力有显着影响。本文描述了包含 α-甲基-L-苯丙氨酸的 Fmoc-二肽的自组装。