This study developed a polymer/layered silicate film as blood‐contacting devices. First, the lecithin‐heparin (LEC‐HEP) was used to modify pristine montmorillonite (MMT). LEC‐HEP was successfully exchanged in the MMT. The organically modified MMT was used for the synthesis of poly(dimethylsiloxane) (PDMS)/MMT‐LEC‐HEP films by intercalation solution technique. The morphological, structural of the prepared film were evaluated using X‐ray diffraction, scanning electron microscopy. LEC‐HEP‐MMT concentration of 0.5 wt% in PDMS systems enhanced mechanical properties. The hemocompatibility of PDMS/LEC‐HEP‐MMT films was evaluated by hemolysis assay, dynamic coagulation time, and plasma recalcification time (PRT). PDMS/0.5 wt% LEC‐HEP‐MMT films also exhibited higher blood anticoagulant indexes, longer the PRT and lower hemolysis rate than the corresponding PDMS film.

中文翻译：

---

具有增强的机械和抗血栓形成特性的蒙脱石-卵磷脂-肝素/ PDMS膜

这项研究开发了一种聚合物/层状硅酸盐薄膜作为血液接触装置。首先，卵磷脂-肝素（LEC-HEP）用于修饰原始蒙脱土（MMT）。LEC-HEP已在MMT中成功交换。有机改性的MMT通过插层溶液技术用于合成聚（二甲基硅氧烷）（PDMS）/ MMT-LEC-HEP膜。使用X射线衍射，扫描电子显微镜对所制备薄膜的形态，结构进行了评估。PDMS系统中LEC‐HEP‐MMT的浓度为0.5 wt％，可提高机械性能。通过溶血测定，动态凝血时间和血浆重钙化时间（PRT）评估PDMS / LEC-HEP-MMT膜的血液相容性。PDMS / 0.5 wt％LEC-HEP-MMT膜还显示出更高的血液抗凝指数，