Quantitative MS-Based Proteomics: Comparing the MCF-7 Cellular Response to Hypoxia and a 2-Oxoglutarate Analogue.,ChemBioChem

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Quantitative MS-Based Proteomics: Comparing the MCF-7 Cellular Response to Hypoxia and a 2-Oxoglutarate Analogue.
ChemBioChem ( IF 2.6 ) Pub Date : 2020-01-10 , DOI: 10.1002/cbic.201900719
Jacob T Bush _{1,

2} , Mun Chiang Chan _{1,

3} , Shabaz Mohammed _{1,

4} , Christopher J Schofield ₁

Affiliation

Coming up for air : We describe MS‐based proteomics studies in which we compared the results of subjecting human breast cancer MCF‐7 cells to hypoxia or treating them with a cell‐penetrating derivative (dimethyl N ‐oxalylglycine) of the stable 2OG analogue N ‐oxalylglycine.

中文翻译：

基于 MS 的定量蛋白质组学：比较 MCF-7 细胞对缺氧和 2-氧戊二酸类似物的反应。

上来呼吸空气：我们描述了基于 MS 的蛋白质组学研究，其中我们比较了人类乳腺癌 MCF-7 细胞缺氧或用稳定 2OG 类似物N的细胞穿透衍生物（二甲基N -草酰甘氨酸）处理的结果‐草酰甘氨酸。

更新日期：2020-01-10

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