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Quantitative MS-Based Proteomics: Comparing the MCF-7 Cellular Response to Hypoxia and a 2-Oxoglutarate Analogue.
ChemBioChem ( IF 3.2 ) Pub Date : 2020-01-10 , DOI: 10.1002/cbic.201900719
Jacob T Bush 1, 2 , Mun Chiang Chan 1, 3 , Shabaz Mohammed 1, 4 , Christopher J Schofield 1
Affiliation  

Coming up for air : We describe MS‐based proteomics studies in which we compared the results of subjecting human breast cancer MCF‐7 cells to hypoxia or treating them with a cell‐penetrating derivative (dimethyl N ‐oxalylglycine) of the stable 2OG analogue N ‐oxalylglycine.
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中文翻译:

基于MS的定量蛋白质组学:比较MCF-7细胞对缺氧和2-氧戊二酸类似物的反应。

出人意料:我们描述了基于MS的蛋白质组学研究,在该研究中,我们比较了使人乳腺癌MCF-7细胞缺氧或用稳定2OG类似物N穿透细胞的衍生物(二甲基N-草酰甘氨酸)对其进行处理的结果。草酰甘氨酸
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更新日期:2020-01-10
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