The solubility of l-alanine in five binary systems water + methanol, water + ethanol, water + 1-propanol, water + 2-propanol, and water + acetone and 12 neat solvents (water, 1-butanol, methanol, 2-butanol, 2-methyl-1-propanol, 1-pentanol, 1-propanol, ethanol, 2-propanol, ethyl acetate, acetonitrile, and acetone) was determined by the gravimetrical method within the temperature range from 283.15 to 323.15 K under atmospheric pressure. The experimental results indicated that the solubility increased with increasing temperature and mole ratio of water in all investigated solvents and decreased with the rise of the mole fraction of five different organic solvents in the binary solvent systems. The order of l-alanine solubility in the selected pure solvents was water > 1-butanol > methanol ≈ 2-butanol > 2-methyl-1-propanol ≈ 1-pentanol ≈ 1-propanol ≈ ethanol > 2-propanol > ethyl acetate > acetonitrile > acetone. The solubility was mathematically represented by the modified Apelblat, Jouyban–Acree, and Apelblat–Jouyban–Acree models. All the models can be found to agree well with the data in the experiment.

中文翻译：

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丙氨酸在二元溶剂和纯溶剂中的溶解度在283.15至323.15 K范围内的测量和相关性

1-丙氨酸在五种二元系统中的溶解度：水+甲醇，水+乙醇，水+ 1-丙醇，水+ 2-丙醇，水+丙酮和12种纯溶剂（水，1-丁醇，甲醇，2-丁醇在大气压下，在283.15至323.15 K的温度范围内通过重量分析法测定2-甲基-1-丙醇，1-戊醇，1-丙醇，乙醇，2-丙醇，乙酸乙酯，乙腈和丙酮。实验结果表明，在二元溶剂体系中，溶解度随温度和水摩尔比的增加而增加，随五种不同有机溶剂摩尔分数的增加而降低。l的顺序-丙氨酸在所选纯溶剂中的溶解度为水> 1-丁醇>甲醇≈2-丁醇> 2-甲基-1-丙醇≈1-戊醇≈1-丙醇≈乙醇> 2-丙醇>乙酸乙酯>乙腈>丙酮。溶解度在数学上用改进的Apelblat，Jouyban-Acree和Apelblat-Jouyban-Acree模型表示。可以发现所有模型都与实验中的数据非常吻合。