Colloidal semiconductor nanocrystals have been extensively used for illumination, displays, bioimaging, and other fields. However, the most extensively used Cd-based nanocrystals are toxic. Recently, non-toxic multinary copper-based chalcogenide semiconductor nanocrystals have been studied intensively. The mostly studied in these materials are ternary Cu–In–S nanocrystals which have large adjustable luminescence range, good luminescence efficiency, and excellent device applications. Therefore, this material has been the most potential candidates to replace Cd-based materials. To date, different synthetic methods have been developed to prepare ternary Cu–In–S nanocrystals, which include hot-injection, non-injection, thermal decomposition, and solvothermal route. In order to enhance the luminescence property, incorporating of Zn²⁺ or overgrowth of a ZnS shell is the comment ways that researchers often use. This review will introduce the synthesis methods of multinary copper-based chalcogenide semiconductor nanocrystals and their potential applications in quantum-dot light-emitting diodes and bioimaging fields. Finally, the conclusion and prospect are provided.

胶体半导体纳米晶体已被广泛用于照明，显示器，生物成像和其他领域。但是，使用最广泛的Cd基纳米晶体是有毒的。最近，对无毒的多元铜基硫族化物半导体纳米晶体进行了深入研究。这些材料中研究最多的是三元Cu-In-S纳米晶体，它们具有可调的发光范围，良好的发光效率和出色的器件应用。因此，这种材料已成为替代基于Cd的材料的最有可能的候选人。迄今为止，已经开发出了不同的合成方法来制备三元Cu-In-S纳米晶体，包括热注入，不注入，热分解和溶剂热途径。为了增强发光性能，掺入锌ZnS壳的²⁺或过度生长是研究人员经常使用的注释方式。本文将介绍多元铜基硫族化物半导体纳米晶体的合成方法及其在量子点发光二极管和生物成像领域的潜在应用。最后，给出了结论和展望。