In this article, the collection of studies with regard to the modeling of nanomanipulation based on atomic force microscope (AFM) is discussed. To model the manipulation process, two-dimensional and three-dimensional models in the classical environment and molecular dynamics can be presented. The decisive factor in determining the solution’s type depends on the dimensions and application of manipulation. In general, however, benefiting from multiscale methods offers more realistic results from the inherent characteristics of AFM point of view. In addition, the manipulation process is examined empirically. Different parameters affect the process. Overall, these include the geometric properties of AFM, geometric properties and material of nanoparticles, process execution environment, initial impact of nanoparticles, contact mechanics, and roughness. The geometric parameters of AFM have less importance compared with other factors. The material and geometry of nanoparticles and environmental reaction play their most dominant role in contact and roughness equations as well as intermolecular forces. For instance, for softer nanoparticles, elastoplastic and viscoelastic contact theories are more suited. In contrast, in environments except vacuum and air, roughness models with more developed adhesion terms are better choices. Employing complex contact theories can provide us with permanent deformations, roughness, reduction in force, and critical indentation depth. In addition to the involved parameters in modeling the nanomanipulation process, path planning techniques for obtaining the optimal path and control of the AFM set for its exact execution are other influential notions.

在本文中，讨论了有关基于原子力显微镜（AFM）进行纳米操作建模的研究。为了对操纵过程建模，可以提出经典环境和分子动力学中的二维和三维模型。确定解决方案类型的决定性因素取决于操作的尺寸和应用。但是，总的来说，从AFM的固有特性来看，受益于多尺度方法可提供更现实的结果。另外，根据经验检查操纵过程。不同的参数会影响过程。总的来说，这些包括原子力显微镜的几何特性，纳米粒子的几何特性和材料，工艺执行环境，纳米粒子的初始冲击，接触力学和粗糙度。与其他因素相比，原子力显微镜的几何参数重要性较低。纳米粒子的材料和几何形状以及环境反应在接触和粗糙度方程以及分子间力中起着最主要的作用。例如，对于较软的纳米粒子，弹塑性和粘弹性接触理论更为合适。相反，在真空和空气以外的环境中，具有更完善的附着力术语的粗糙度模型是更好的选择。采用复杂的接触理论可以为我们提供永久的变形，粗糙度，力的减小和临界压痕深度。除了对纳米操纵过程进行建模所涉及的参数外，用于获得AFM最佳路径并对其进行精确控制的路径规划技术也是其他有影响力的概念。