The implications of chirality in different environments are already well known and reported extensively in the literature. Capillary Electrophoresis, a separation technique that only requires few nanoliters of sample, has demonstrated its potential for chiral analysis in the past years. The aim of this article is to provide an overview on the fundamentals and characteristics of Chiral Capillary Electrophoresis as well as the main advances and trends in this topic. Special attention is paid to the most recent technological and methodological developments achieved mainly in the most employed separation mode (Electrokinetic Cromatography). The most noteworthy and recent applications reported on the enantiomeric separation and determination of compounds in pharmaceutical, food, biomedical, environmental or forensic samples will also be critically overviewed. The characteristics of the developed methodologies will be detailed in Tables and future trends will also be discussed.

在不同环境中手性的含义已经众所周知，并且在文献中被大量报道。毛细管电泳是一种仅需几纳升样品的分离技术，在过去的几年中证明了其手性分析的潜力。本文的目的是概述手性毛细管电泳的基本原理和特性，以及该主题的主要进展和趋势。特别注意主要在最常用的分离模式（电动层析）中获得的最新技术和方法发展。关于药物，食品，生物医学，还将对环境或法医样品进行严格概述。表中将详细介绍已开发方法的特征，还将讨论未来趋势。