BACKGROUND Obsessive compulsive disorder (OCD) is a chronic mental health condition recognized as one of the most serious causes of disability and impaired quality of life. In the literature, there is no review about sexual dysfunction and satisfaction in OCD. The current paper presents the protocol for a systematic review and meta-analysis aimed to summarize data (1) comparing the presence of sexual dysfunction between groups with OCD and non-clinical groups, (2) investigating prevalence of each one of the sexual dysfunctions in patients with OCD, (3) comparing risk for sexual dysfunction in OCD groups with the prevalence in control groups, (4) comparing sexual satisfaction between OCD groups and non-clinical groups, and (5) investigating moderators of sexual dysfunction in OCD groups as compared with control groups. Gender, age, marital status, OCD symptom severity and subtypes, comorbid depressive disorders, comorbid anxiety disorders, concurrent psychiatric medications, comorbid general medical disease, and study quality will be investigated as moderators. METHODS The protocol is reported according to PRISMA-P guidelines. The search will be conducted by independent reviewers during the second week of December 2019 by using electronic databases (Scopus, PubMed, EMBASE, PsycINFO, CINAHL, and the Cochrane Library), by contacting the authors of the included studies to identify further data, by examining the references of the included studies, and by handsearching conference proceedings and theses/doctoral dissertations. The study quality will be independently evaluated using the Newcastle-Ottawa Quality Assessment Scale. Random-effect meta-analyses will be computed. If there is insufficient data for a specific outcome, only a systematic review will be performed. DISCUSSION This review may support clinical practice highlighting the importance of the assessment of sexuality in patients with OCD and suggesting the use of therapeutic strategies dedicated to sexuality in this clinical population with the aim of improving patients' quality of life. Potential limitations will regard the heterogeneity of the studies in terms of the instruments used to assess sexual dysfunction/satisfaction and of the definitions used to conceptualize sexual dysfunction. SYSTEMATIC REVIEW REGISTRATION Prospero CRD42019132264.

中文翻译：

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强迫症的性功能障碍和满意度：系统评价和荟萃分析方案。

背景技术强迫症（OCD）是一种慢性精神健康状况，被认为是导致残疾和生活质量受损的最严重原因之一。文献中尚未对强迫症患者的性功能障碍和满意度进行综述。本文提出了系统评价和荟萃分析的方案，旨在总结数据（1）比较强迫症组和非临床组之间性功能障碍的存在情况，（2）调查每一种性功能障碍的患病率强迫症患者，（3）比较强迫症组性功能障碍的风险与对照组的患病率，（4）比较强迫症组和非临床组之间的性满意度，（5）调查强迫症组性功能障碍的调节因素与对照组相比。性别、年龄、婚姻状况、强迫症症状严重程度和亚型、共病抑郁症、共病焦虑症、并发精神科药物、共病一般医学疾病和研究质量将作为调节因素进行调查。方法 根据 PRISMA-P 指南报告方案。独立审稿人将于 2019 年 12 月第二周使用电子数据库（Scopus、PubMed、EMBASE、PsycINFO、CINAHL 和 Cochrane 图书馆）进行检索，并联系纳入研究的作者以确定更多数据，检查纳入研究的参考文献，并手动检索会议记录和论文/博士论文。研究质量将使用纽卡斯尔-渥太华质量评估量表进行独立评估。将计算随机效应荟萃分析。如果特定结果的数据不足，则仅进行系统评价。讨论 本综述可能支持临床实践，强调强迫症患者性行为评估的重要性，并建议在该临床人群中使用专门针对性行为的治疗策略，以改善患者的生活质量。潜在的局限性在于这些研究在评估性功能障碍/满意度的工具以及用于概念化性功能障碍的定义方面存在异质性。系统审查注册 Prospero CRD42019132264。