BACKGROUND We report a case of uveitis-glaucoma-hyphema (UGH) syndrome in a highly myopic pseudophakic eye with seemingly normal positioning of a two-haptic intraocular lens (IOL). CASE PRESENTATION The patient was a 61-year-old woman suffering recurrent episodes of blurred vision, floaters, redness, elevated intraocular pressure (IOP), and pain in the right eye following implantation of a sclera-fixed IOL. The symptoms were alleviated by the systemic and topical administration of IOP-lowering and anti-inflammatory medications. A slit-lamp examination revealed depigmentation and atrophy of the iris, and a quiet anterior chamber in the right eye. Endophthalmitis caused by hypovirulent bacteria and UGH syndrome were both considered. Ultrasound biomicroscopy (UBM) and gonioscopy provided direct evidence of malpositioned IOL haptics, which pushed the root of the iris forward, resulting in persistent mechanical chaffing, the probable cause of UGH syndrome. IOL explantation resolved her symptoms. Negative bacterial culture results for the IOL excluded the possibility of endophthalmitis. CONCLUSIONS Heightened awareness of underlying UGH syndrome and prompt UBM are important when doctors encounter a patient with a sclera-fixed IOL suffering from recurrent anterior segment inflammation and elevated IOP.

中文翻译：

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高度近视眼中巩膜固定的后房两触眼人工晶状体的葡萄膜炎-青光眼-前房综合征：一例病例报告。

背景我们报道了高度近视假晶状体眼中葡萄膜炎-青光眼-眼角膜下垂（UGH）综合征的情况，该假眼具有两触觉人工晶状体（IOL）的正常定位。病例介绍该患者是一名61岁的女性，在植入巩膜固定的IOL后，经常出现视力模糊，漂浮，发红，眼压升高（IOP）和右眼疼痛的发作。通过降低眼压和消炎药的全身和局部给药缓解了症状。裂隙灯检查发现虹膜色素沉着和萎缩，右眼前房安静。都考虑了由低毒细菌引起的眼内炎和UGH综合征。超声生物显微镜（UBM）和测角镜可提供IOL触觉位置不正确的直接证据，从而将虹膜的根部向前推，导致持续的机械摩擦，这可能是UGH综合征的原因。人工晶体外植可缓解她的症状。IOL细菌培养阴性结果排除了眼内炎的可能性。结论当医生遇到患有巩膜固定性IOL的患者患有复发性前节炎症和IOP升高时，提高对潜在UGH综合征的认识和及时进行UBM至关重要。