Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T.,European Journal of Heart Failure

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Circulating levels and prognostic value of soluble ST2 in heart failure are less influenced by age than N-terminal pro-B-type natriuretic peptide and high-sensitivity troponin T.
European Journal of Heart Failure ( IF 16.9 ) Pub Date : 2020-01-09 , DOI: 10.1002/ejhf.1701
Alberto Aimo ₁ , James L Januzzi ₂ , Giuseppe Vergaro _{1,

3} , A Mark Richards ₄ , Carolyn S P Lam ₅ , Roberto Latini ₆ , Inder S Anand _{7,

8} , Jay N Cohn ₇ , Thor Ueland _{9,

10,

11} , Lars Gullestad ₁₀ , Pål Aukrust ₁₀ , Hans-Peter Brunner-La Rocca ₁₂ , Antoni Bayes-Genis ₁₃ , Josep Lupón ₁₃ , Rudolf A de Boer ₁₄ , Yasuchika Takeishi ₁₅ , Michael Egstrup ₁₆ , Ida Gustafsson ₁₆ , Hanna K Gaggin ₂ , Kai M Eggers ₁₇ , Kurt Huber ₁₈ , Greg D Gamble ₁₉ , Lieng H Ling ₅ , Kui Tong Gerard Leong ₂₀ , Poh Shuah Daniel Yeo ₂₁ , Hean Yee Ong ₂₂ , Fazlur Jaufeerally ₂₃ , Tze P Ng ₅ , Richard Troughton ₂₄ , Robert N Doughty ₁₉ , Claudio Passino _{3,

4} , Michele Emdin _{3,

4}

Affiliation

Scuola Superiore Sant'Anna, Pisa, Italy.
Massachusetts General Hospital and Baim Institute for Clinical Research, Boston, MA, USA.
Fondazione Toscana G. Monasterio, Pisa, Italy.
University of Otago, Dunedin, New Zealand.
National University of Singapore, Singapore.
IRCCS - Istituto di Ricerche Farmacologiche 'Mario Negri', Milan, Italy.
University of Minnesota, Minneapolis, MN, USA.
VA Medical Centre, Minneapolis, MN, USA.
Oslo University Hospital, Oslo, Norway.
University of Oslo, Oslo, Norway.
University of Tromsø, Tromsø, Norway.
Maastricht University Medical Centre, Maastricht, The Netherlands.
Hospital Universitari Germans Trias i Pujol, Badalona (Barcelona) and CIBER Cardiovascular, Instituto de Salud Carlos III, Madrid, Spain.
University Medical Centre Groningen, Groningen, The Netherlands.
Fukushima Medical University, Fukushima, Japan.
Copenhagen University Hospital Rigshospitalet, Copenhagen, Denmark.
Uppsala University, Uppsala, Sweden.
Wilhelminenspital and Sigmund Freud University Medical School, Vienna, Austria.
University of Auckland, Auckland, New Zealand.
Changi General Hospital, Singapore.
Tan Tock Seng Hospital, Singapore.
Khoo Teck Puat Hospital, Singapore.
Singapore General Hospital, Singapore.
University of Otago, Christchurch, New Zealand.

N‐terminal pro‐B‐type natriuretic peptide (NT‐proBNP), high‐sensitivity troponin T (hs‐TnT) and soluble suppression of tumorigenesis‐2 (sST2) predict outcome in chronic heart failure (HF). We assessed the influence of age on circulating levels and prognostic significance of these biomarkers.

中文翻译：

可溶性ST2在心力衰竭中的循环水平和预后价值受年龄的影响要小于N端pro-B型利钠肽和高敏感性肌钙蛋白T。

N端前B型利尿钠肽（NT-proBNP），高敏感性肌钙蛋白T（hs-TnT）和可抑制肿瘤发生-2（sST2）可以预测慢性心力衰竭（HF）的预后。我们评估了年龄对这些生物标志物循环水平和预后意义的影响。

更新日期：2020-01-09

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