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Enhanced corrosion resistance and biocompatibility of magnesium alloy by hydroxyapatite/graphene oxide bilayer coating
Materials Letters ( IF 3 ) Pub Date : 2020-04-01 , DOI: 10.1016/j.matlet.2020.127322
Feng Peng , Dongdong Zhang , Donghui Wang , Lidan Liu , Yu Zhang , Xuanyong Liu

Abstract Fast degradation is the major limitation for biomedical application of Mg alloy. In the current work, a bilayer coating (HA/GO#) with hydroxyapatite as the inner layer and graphene oxide as the out layer was prepared on AZ31 alloy. Graphene oxide could sufficiently inhibit the formation and growth of corrosion cracks on hydroxyapatite layer, which result in its superior corrosion resistance. In vitro cell viability results suggested that MC3T3-E1 cells exhibited larger spreading area on HA/GO# coating at the initial 4 h of incubation. Furthermore, cells on HA/GO# coating showed superior proliferation rate. Considering its satisfied corrosion resistance and biocompatibility, the as prepared bilayer coating on AZ31 alloy is promising for clinical application.

中文翻译:

通过羟基磷灰石/氧化石墨烯双层涂层增强镁合金的耐腐蚀性和生物相容性

摘要 快速降解是镁合金生物医学应用的主要限制。在目前的工作中,在 AZ31 合金上制备了以羟基磷灰石为内层、氧化石墨烯为外层的双层涂层 (HA/GO#)。氧化石墨烯可以充分抑制羟基磷灰石层腐蚀裂纹的形成和生长,使其具有优异的耐腐蚀性能。体外细胞活力结果表明,MC3T3-E1 细胞在孵育的最初 4 小时在 HA/GO# 涂层上表现出更大的铺展面积。此外,HA/GO#涂层上的细胞显示出优异的增殖率。考虑到其令人满意的耐腐蚀性和生物相容性,所制备的 AZ31 合金双层涂层有望用于临床应用。
更新日期:2020-04-01
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