BACKGROUND Inflammation is the hallmark of coronary artery disease (CAD) and CTD. There are reports of increased prevalence of CAD among patients with CTD such as Rheumatoid Arthritis. However, there is a paucity of data regarding the outcomes of PCI among patients with CTD. METHODS Using the National Inpatient Database, patients that underwent PCI between 2007 and 2015 were identified using ICD-9-CM codes. Propensity match analysis with 1: 3 matching of patients with and without CTD was performed. Outcomes were acute kidney injury (AKI), access site complication (ASC), ventricular fibrillation (VF), cardiogenic shock (CS), Stroke, In-hospital mortality and hospital length of stay (LOS) compared between both groups. RESULT We identified 17,422 patients with CTD and matched with 52, 266 patients without CTD. Patients were predominantly female (63.1%) and white (77.2%), with a mean age of 63 ± 12.1 years. AKI (8.3% vs. 6.6%, p < 0.001), ASC (3.2% vs. 2.7%, p = 0.01) and hospital stay (4.2 ± 4.8 vs. 3.8 ± 5.2, p < 0.001) were higher among patients with CTD. There was no statistically significant difference in rates of VF, CS, stroke, and In-hospital mortality among the two groups. However, in subgroup analysis, rates of VF were lower among patients with Systemic Lupus Erythematosus (SLE) (1.5% vs. 2.2%, p = 0.006). CONCLUSIONS Patients with CTD undergoing PCI have a higher rate of AKI, Access site complications, and prolonged hospital stay.

中文翻译：

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结缔组织疾病患者中经皮冠状动脉介入治疗（PCI）的结果：倾向匹配分析。

背景技术炎症是冠状动脉疾病（CAD）和CTD的标志。有报告说，类风湿关节炎等CTD患者的CAD患病率增加。但是，关于CTD患者中PCI结局的数据很少。方法使用国家住院数据库，使用ICD-9-CM代码识别2007年至2015年接受PCI的患者。进行了具有和不具有CTD的患者的1：3匹配的倾向匹配分析。两组患者的结果分别为急性肾损伤（AKI），进入部位并发症（ASC），心室纤颤（VF），心源性休克（CS），中风，住院死亡率和住院时间（LOS）。结果我们确定了17,422例CTD患者，与52例266例无CTD患者相匹配。患者主要为女性（63。1％）和白人（77.2％），平均年龄为63±12.1岁。CTD患者的AKI（8.3％vs. 6.6％，p <0.001），ASC（3.2％vs. 2.7％，p = 0.01）和住院时间（4.2±4.8 vs. 3.8±5.2，p <0.001）更高。两组之间的VF，CS，中风和住院死亡率无统计学差异。但是，在亚组分析中，系统性红斑狼疮（SLE）患者的VF率较低（1.5％比2.2％，p = 0.006）。结论接受PCI的CTD患者的AKI发生率，进入部位并发症和住院时间较长。两组之间的VF，CS，中风和住院死亡率无统计学差异。但是，在亚组分析中，系统性红斑狼疮（SLE）患者的VF率较低（1.5％比2.2％，p = 0.006）。结论接受PCI的CTD患者的AKI发生率，进入部位并发症和住院时间较长。两组之间的VF，CS，中风和住院死亡率无统计学差异。但是，在亚组分析中，系统性红斑狼疮（SLE）患者的VF率较低（1.5％比2.2％，p = 0.006）。结论接受PCI的CTD患者的AKI发生率，进入部位并发症和住院时间较长。