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A turn-on luminescence probe for highly selective detection of an anthrax biomarker.
Luminescence ( IF 3.2 ) Pub Date : 2020-01-08 , DOI: 10.1002/bio.3764
Xiao Liu 1 , Dong Chen 2 , Chenchen Wang 1 , Nianjuan Tian 1 , Zhiqiang Li 1 , Ying Zhang 1 , Zhi-Jun Ding 2
Affiliation  

Highly selective detection of Bacillus anthrax spores has attracted worldwide attention because Bacillus anthrax spores not only are harmful to the health of human beings and animals, but also can be used as biological warfare agents. Here, we report a simple platform by mixing EuCl3 ·6H2 O and sodium polyacrylate in aqueous solution and further investigate its luminescence response towards Bacillus anthrax biomarker dipicolinic acid (DPA) as a turn-on luminescence probe. Importantly, our probe has good sensitivity, lower detection limit, excellent selectivity as well as great anti-interference ability due to the great luminescence enhancement of Eu3+ . Moreover, a test paper is constructed to realize the purpose of portable detection. These results indicate that our probe is an excellent candidate for sensing DPA.

中文翻译:

开启式荧光探针,用于炭疽生物标志物的高度选择性检测。

由于炭疽杆菌芽孢不仅对人类和动物的健康有害,而且可以用作生物战剂,因此对炭疽芽孢杆菌孢子的高选择性检测已引起了全世界的关注。在这里,我们报告了一个简单的平台,将EuCl3·6H2 O和聚丙烯酸钠在水溶液中混合,并进一步研究了其对芽孢杆菌炭疽生物标志物二吡啶甲酸(DPA)的发光响应,作为开启发光探针。重要的是,由于Eu3 +的发光增强,我们的探针具有良好的灵敏度,较低的检测限,出色的选择性以及出色的抗干扰能力。此外,构造试纸以实现便携式检测的目的。这些结果表明我们的探针是检测DPA的极佳候选者。
更新日期:2020-01-08
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