Careful study of T-cell clonal dynamics in patients with non-small cell lung cancer treated with neoadjuvant nivolumab suggests that successful trafficking of clones from a proliferative burst in the periphery to the tumor associates with major pathologic response. Integration of these findings with functional analysis may augment current therapeutic strategies.See related article by Zhang et al., p. XXX.

中文翻译：

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优秀的肿瘤内T细胞克隆型（1％）影响“ Tri滴细胞毒性”。

对新辅助药nivolumab治疗的非小细胞肺癌患者的T细胞克隆动力学进行的仔细研究表明，克隆的成功运输是从外周的增生性爆发转移至肿瘤，这与主要的病理反应有关。这些发现与功能分析的整合可能会增强当前的治疗策略。XXX。