BACKGROUND Pulse oximetry is widely used in the clinical setting. The purpose of this validation study was to investigate the level of agreement between oxygen saturations measured by pulse oximeter (SpO2) and arterial blood gas (SaO2) in a range of oximeters in clinical use in Australia and New Zealand. METHODS Paired SpO2 and SaO2 measurements were collected from 400 patients in one Australian and two New Zealand hospitals. The ages of the patients ranged from 18 to 95 years. Bias and limits of agreement were estimated. Sensitivity and specificity for detecting hypoxaemia, defined as SaO2 < 90%, were also estimated. RESULTS The majority of participants were recruited from the Outpatient, Ward or High Dependency Unit setting. Bias, oximeter-measured minus arterial blood gas-measured oxygen saturation, was - 1.2%, with limits of agreement - 4.4 to 2.0%. SpO2 was at least 4% lower than SaO2 for 10 (2.5%) of the participants and SpO2 was at least 4% higher than the SaO2 in 3 (0.8%) of the participants. None of the participants with a SpO2 ≥ 92% were hypoxaemic, defined as SaO2 < 90%. There were no clinically significant differences in oximetry accuracy in relation to clinical characteristics or oximeter brand. CONCLUSIONS In the majority of the participants, pulse oximetry was an accurate method to assess SaO2 and had good performance in detecting hypoxaemia. However, in a small proportion of participants, differences between SaO2 and SpO2 could have clinical relevance in terms of patient monitoring and management. A SpO2 ≥ 92% indicates that hypoxaemia, defined as a SaO2 < 90%, is not present. TRIAL REGISTRATION Australian and New Zealand Clinical Trials Registry (ACTRN12614001257651). Date of registration: 2/12/2014.

中文翻译：

---

一项多中心前瞻性观察性研究，比较了在澳大利亚和新西兰医院的成年患者中使用的动脉血氧饱和度测定仪与脉搏血氧仪获得的值。

背景技术脉搏血氧饱和度在临床环境中被广泛使用。这项验证研究的目的是调查在澳大利亚和新西兰临床使用的一系列血氧仪中，通过脉搏血氧仪（SpO2）和动脉血气（SaO2）测量的氧饱和度之间的一致性水平。方法成对的SpO2和SaO2的测量是从一所澳大利亚和新西兰两家医院的400例患者中收集的。患者的年龄为18至95岁。估计偏差和协议限制。还估计了检测低氧血症的敏感性和特异性，定义为SaO2 <90％。结果大多数参与者是从门诊，病房或高依赖病房设置中招募的。用血氧仪测得的负值减去动脉血气测得的血氧饱和度的偏差为-1.2％，一致限-4。4至2.0％。10名参与者（2.5％）的SpO2比SaO2低至少4％，而3名参与者（0.8％）的SpO2比SaO2高至少4％。SpO2≥92％的参与者均无低氧血症，即SaO2 <90％。血氧定量准确度与临床特征或血氧饱和度计品牌没有临床显着差异。结论在大多数参与者中，脉搏血氧饱和度是评估SaO2的准确方法，在检测低氧血症方面具有良好的性能。但是，在一小部分参与者中，SaO2和SpO2之间的差异在患者监测和管理方面可能具有临床意义。SpO2≥92％表示不存在低氧血症，定义为SaO2 <90％。试验注册澳大利亚和新西兰临床试验注册（ACTRN12614001257651）。注册日期：2014年2月12日。