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Osteogenic Hydrogels: Gelatin Templated Polypeptide Co‐Cross‐Linked Hydrogel for Bone Regeneration (Adv. Healthcare Mater. 1/2020)
Advanced Healthcare Materials ( IF 10.0 ) Pub Date : 2020-01-08 , DOI: 10.1002/adhm.202070001
Yusen Qiao 1 , Xingzhi Liu 1 , Xichao Zhou 1 , Hongbo Zhang 2, 3 , Wen Zhang 1 , Wei Xiao 4 , Guoqing Pan 5 , Wenguo Cui 2 , Hélder A. Santos 6, 7 , Qin Shi 1
Affiliation  

In article number 1901239 by Wenguo Cui, Hélder A. Santos, Qin Shi, and co‐workers, a photo‐crosslinked osteogenic growth peptide is constructed by solid‐state synthesis, and then co‐crosslinked with photo‐crosslinked gelatin by UV‐radiation to create a novel osteogenic polypeptide hydrogel to promote long term bone regeneration. The co‐crosslinked polypeptide can strengthen the mechanical property of the defect bone and avoid burst osteogenic peptides, releasing during the bone defect healing period.
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中文翻译:

成骨水凝胶:用于骨骼再生的明胶模板化多肽共交联水凝胶(Adv。Healthcare Mater。1/2020)

崔文国,HélderA.Santos,Qin Shi和同事的文章编号1901239中,通过固态合成构建了光交联的成骨生长肽,然后通过紫外线辐射将其与光交联的明胶共交联。创建一种新型的成骨多肽水凝胶,以促进长期的骨再生。共交联的多肽可以增强缺损骨骼的机械性能,并避免在骨骼缺损愈合期间释放破裂的成骨肽。
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更新日期:2020-01-08
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