BACKGROUND Adverse birth outcome which attributes to most perinatal deaths is an important indicator of child health and survival. Hence, this study aims to identify determinants of adverse birth outcome among mothers who gave birth in public hospitals of Tigrai region, North Ethiopia. METHODS Hospital based case-control study was conducted in Tigrai region, Ethiopia between December 2015 and January 2016 among 405 (135 cases and 270 controls) consecutively selected mothers who gave birth in four randomly selected public Hospitals. Mothers with adverse birth outcome (preterm birth; < 37 gestational weeks at birth, low birth weight; < 2.5 kg at birth, or still birth) were the cases while mothers without adverse birth outcome (live birth, birth weight ≥ 2.5 kg and of ≥37 gestational weeks at birth) were the controls. Data were collected by interview and reviewing medical records using structured questionnaire. The collected data were entered into database using EPI info version 3.5.1 then exported to SPSS version 21 for analysis. Finally, multivariate logistic regression was used to identify determinants of adverse birth outcomes at P value < 0.05. RESULT The mean age of cases and controls was 27.3 (SD = 6.6) and 26.14 (SD = 4.9) years, respectively. In a multivariate analysis; less than four antenatal care visits [AOR = 4.35, 95% CI: 1.15-13.50], not receiving dietary counseling [AOR = 11.24, 95% CI: 3.92-36.60], not using family planning methods [AOR = 4.06, 95% CI:1.35-17.34], less than 24 months inter pregnancy interval [AOR = 5.21, 95% CI: 1.89-13.86], and less than 11 g/dl hemoglobin level [AOR = 4.86, 95% CI: 1.83-14.01] were significantly associated with adverse birth outcomes. CONCLUSION AND RECOMMENDATION The number of antenatal care visits, ever use of family planning methods, not receiving dietary counseling during antenatal care follow up visits, short inter-pregnancy interval, and low hemoglobin level were identified as independent determinants of adverse birth outcome. A concerted effort should be taken improve family planning use, and antenatal care follow-up with special emphasis to maternal nutrition to prevent adverse birth outcomes.

中文翻译：

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埃塞俄比亚北部提格莱地区不良出生结局的决定因素：以医院为基础的病例对照研究。


背景技术不良出生结局是大多数围产期死亡的原因，是儿童健康和生存的重要指标。因此，本研究旨在确定在埃塞俄比亚北部提格莱地区公立医院分娩的母亲不良分娩结局的决定因素。方法 2015 年 12 月至 2016 年 1 月期间，在埃塞俄比亚提格莱地区进行了以医院为基础的病例对照研究，连续选取了 4 家随机选择的公立医院分娩的 405 名母亲（135 名病例和 270 名对照）。不良分娩结局的母亲（早产、出生孕周<37周、低出生体重、出生时体重<2.5公斤或死产）是指母亲，而无不良分娩结局的母亲（活产、出生体重≥2.5公斤和出生时≥37孕周）为对照。通过访谈和使用结构化问卷审查病历来收集数据。收集的数据使用 EPI info 3.5.1 版输入数据库，然后导出到 SPSS 21 版进行分析。最后，使用多变量逻辑回归来确定 P 值 < 0.05 时不良出生结果的决定因素。结果 病例和对照的平均年龄分别为 27.3 (SD = 6.6) 和 26.14 (SD = 4.9) 岁。在多变量分析中；产前检查次数少于四次 [AOR = 4.35，95% CI：1.15-13.50]，未接受饮食咨询 [AOR = 11.24，95% CI：3.92-36.60]，未使用计划生育方法 [AOR = 4.06，95% CI：1.35-17.34]，妊娠间隔少于 24 个月 [AOR = 5.21，95% CI：1.89-13.86]，血红蛋白水平低于 11 g/dl [AOR = 4.86，95% CI：1.83-14.01]与不良分娩结局显着相关。 结论和建议产前保健次数、曾经使用计划生育方法、产前保健随访期间未接受饮食咨询、妊娠间隔短和血红蛋白水平低被认为是不良出生结局的独立决定因素。应共同努力改善计划生育的使用和产前保健随访，特别强调孕产妇营养，以防止不良出生结果。