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Antibacterial performance of glucose-fructose added MW based zirconia coatings - Possible treatment for bone infection.
Journal of the Mechanical Behavior of Biomedical Materials ( IF 3.3 ) Pub Date : 2020-01-08 , DOI: 10.1016/j.jmbbm.2020.103621
Ifra Sanaullah 1 , Bushra S Bukhari 1 , Tanzeela Batool 1 , Saira Riaz 1 , Hira N Khan 2 , Anjum N Sabri 2 , Shahzad Naseem 1
Affiliation  

Use of ceramic coatings has increased dramatically in orthopedics by improving their wear resistance and consequent long-term stability. Such stability involves not only the strength of material but also its resistance toward bacterial attacks. Amongst all ceramics, zirconia is selected in the present study due to its white color and high value of hardness making it a potential candidate to be used as implants and their coatings. In the present study effect of varying microwave powers (i.e. 100W, 200W, 300W, 400W, 500W, 600W, 700W, 800W, 900W and 1000W) on sol–gel synthesized glucose and fructose added zirconia coatings has been investigated. Formation of mixed tetragonal – monoclinic phases has been observed at relatively low microwave powers, i.e. 100–500W. However, at 600–1000W phase pure tetragonal zirconia is observed without any post heat treatment. FTIR analysis confirms formation of tetragonal phase of zirconia at 600–1000W microwave power. XPS results confirm the binding energies of Zr 3d and O 1s of microwave assisted zirconia coatings. High value of transmittance, i.e. ~90%, is observed at higher microwave powers. Variation in microwave powers is observed to tune the energy band gap of zirconia coatings in the range of 4.2–5.1 eV. Dielectric constant of 8–10 at log f = 4 is observed. High value of hardness and fracture toughness i.e. 1231 HV and 24.85 MPam−1/2, respectively, is observed for stabilized tetragonal zirconia coatings. Stabilized glucose fructose added zirconia shows strong antioxidant activity. Zirconia coatings are tested against Staphylococcus aureus bacteria for their potential application to treat bone infection. Results suggest that stabilized tetragonal zirconia can be successfully employed for orthopedic coatings.



中文翻译:

葡萄糖基果糖添加的基于MW的氧化锆涂层的抗菌性能-骨感染的可能治疗方法。

通过改善陶瓷涂层的耐磨性和长期稳定性,陶瓷涂层的使用已显着增加。这种稳定性不仅涉及材料的强度,还涉及其对细菌侵袭的抵抗力。在所有陶瓷中,氧化锆由于其白色和高硬度值而在本研究中被选中,这使其有可能用作植入物及其涂层。在本研究中,已经研究了各种微波功率(即100W,200W,300W,400W,500W,600W,700W,800W,900W和1000W)对溶胶-凝胶合成的葡萄糖和果糖添加氧化锆涂层的影响。在相对较低的微波功率(即100–500W)下,观察到了混合的四方-单斜晶相的形成。然而,在600–1000W相下,无需任何后热处理即可观察到纯四方氧化锆。FTIR分析证实了在600–1000W微波功率下氧化锆的四方相的形成。XPS结果证实了微波辅助氧化锆涂层的Zr 3d和O 1s的结合能。在较高的微波功率下观察到较高的透射率值,即〜90%。观察到微波功率的变化可将氧化锆涂层的能带隙调整为4.2–5.1 eV。对数常数为8-10 观察到微波功率的变化可将氧化锆涂层的能带隙调整为4.2–5.1 eV。对数常数为8-10 观察到微波功率的变化可将氧化锆涂层的能带隙调整为4.2–5.1 eV。对数常数为8-10f  = 4。对于稳定的四方氧化锆涂层,观察到较高的硬度和断裂韧性值,即分别为1231 HV和24.85 MPam -1/2。添加氧化锆的稳定葡萄糖果糖显示出强大的抗氧化活性。氧化锆涂层针对金黄色葡萄球菌进行了测试,以探讨其在治疗骨骼感染中的潜在用途。结果表明,稳定的四方氧化锆可成功用于骨科涂层。

更新日期:2020-01-08
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