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Endocytosis, cadherins and tissue dynamics.
Traffic ( IF 3.6 ) Pub Date : 2020-01-07 , DOI: 10.1111/tra.12721
Hiroko Katsuno-Kambe 1 , Alpha S Yap 1
Affiliation  

By happy chance, the founding of Traffic in 1999 coincided with a clutch of reports that documented the endocytosis and recycling of classical cadherin adhesion receptors. This stimulated a concerted effort to elucidate the molecular regulation of cadherin endocytosis and to identify its functional implications. In particular, endocytosis provided new perspectives to understand how cadherins are modulated during tissue morphogenesis. In this short article, we consider some of what we have learnt about this problem and identify open questions for future research.

中文翻译:

内吞,钙黏着蛋白和组织动力学。

幸运的是,Traffic于1999年成立,同时有大量报道记录了经典钙粘蛋白粘附受体的内吞作用和回收利用。这激发了共同努力,阐明了钙粘蛋白内吞作用的分子调控并确定其功能含义。特别地,胞吞作用提供了新的观点,以了解钙粘蛋白在组织形态发生过程中如何被调节。在这篇简短的文章中,我们将考虑一些有关此问题的知识,并确定未解决的问题,以备将来研究之用。
更新日期:2020-02-18
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