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A New Synthesis of l-Hydroxypipecolic Acid
Synlett ( IF 1.7 ) Pub Date : 2020-01-07 , DOI: 10.1055/s-0039-1690771 Zedong Zhang , Zhihua Sun 1
Synlett ( IF 1.7 ) Pub Date : 2020-01-07 , DOI: 10.1055/s-0039-1690771 Zedong Zhang , Zhihua Sun 1
Affiliation
A new synthetic approach toward l -hydroxypipecolic acid is described. This reaction sequence involves eight steps overall, starting from commercially available and inexpensive l -glyceraldehyde acetal. The strategy makes use of readily available reagents and can be used as a preparative synthesis of l -hydroxypipecolic acid. Most of the reaction steps proceed with moderate-to-good yields and do not require any unusual or expensive reagents.
中文翻译:
l-羟基哌啶酸的新合成
描述了一种新的 l-羟基哌啶酸合成方法。该反应序列总共包括八个步骤,从市售且廉价的 l-甘油醛缩醛开始。该策略利用容易获得的试剂,可用作 l-羟基哌啶酸的制备性合成。大多数反应步骤以中等至良好的产率进行,不需要任何不寻常或昂贵的试剂。
更新日期:2020-01-07
中文翻译:
l-羟基哌啶酸的新合成
描述了一种新的 l-羟基哌啶酸合成方法。该反应序列总共包括八个步骤,从市售且廉价的 l-甘油醛缩醛开始。该策略利用容易获得的试剂,可用作 l-羟基哌啶酸的制备性合成。大多数反应步骤以中等至良好的产率进行,不需要任何不寻常或昂贵的试剂。