BACKGROUND Effective transdiagnostic treatments for patients presenting with principal or comorbid symptoms of anxiety and depression enable more efficient provision of mental health care and may be particularly suitable for the varied population seen in primary healthcare settings. Mindfulness-integrated cognitive behavior therapy (MiCBT) is a transdiagnostic intervention that integrates aspects of CBT, including exposure skills targeting avoidance, with training in mindfulness meditation skills adopted from the Vipassana or insight tradition taught by the Burmese teachers U Ba Khin and Goenka. MiCBT is distinguished from both cognitive therapy and mindfulness-based cognitive therapy by the use of a theoretical framework which proposes that the locus of reinforcement of behavior is the interoceptive experience (body sensations) that co-arises with self-referential thinking. Consequently, MiCBT has a strong focus on body scanning to develop interoceptive awareness and equanimity. Designed for clinical purposes, the four-stage systemic approach of MiCBT, comprising intra-personal (Stage 1) exposure (Stage 2), interpersonal (Stage 3), and empathic (Stage 4) skillsets, is a distinguishing feature among other mindfulness-based interventions (MBIs). The aim of this study is to investigate whether and how group MiCBT decreases depression and anxiety symptoms for patients with a range of common mental health conditions. METHODS Participants (n = 120) recruited via medical practitioner referral will be randomized to MiCBT or a wait-list control. Inclusion criteria are age 18-75; fluent in English and having a Kessler Psychological Distress Scale (K10) score of 20 or more. The MiCBT treatment group receive an 8-week MiCBT intervention delivered in a private psychology practice. Participants complete a suite of online self-report measures and record the amount of meditation practice undertaken each week. The control group receive usual treatment and complete the measures at the same time points. Primary outcome measures are the Depression Anxiety Stress Scale-21 (DASS-21) and K10. Analysis will use mixed-model repeated measures. DISCUSSION The potential ability of MiCBT to provide a comprehensive therapeutic system that is applicable across diagnostic groups would make it an attractive addition to the available MBIs. TRIAL REGISTRATION This trial is registered with the Australia and New Zealand Clinical Trials Registry: ACTRN12617000061336; Date of registration: 11th January 2017.

中文翻译：

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一项随机对照试验的研究方案，以调查为期8周的正念综合认知行为疗法（MiCBT）转诊组对基层医疗患者的有效性。

背景技术对于表现出焦虑和抑郁的主要症状或合并症的患者的有效的转诊治疗使得能够更有效地提供精神保健，并且可能特别适合于在初级保健环境中看到的各种人群。正念综合认知行为疗法（MiCBT）是一种跨诊断性干预措施，结合了CBT的各个方面，包括针对避免接触的暴露技能，以及内观禅修技能的培训，这些修养方法来自内观或缅甸老师U Ba Khin和Goenka教授的洞察力传统。通过使用一个理论框架，MiCBT与认知疗法和基于正念的认知疗法都不同，该理论框架认为，行为强化的源头是与自我参照思维共同产生的互感体验（身体感觉）。因此，MiCBT十分注重身体扫描，以提高感知觉意识和镇静作用。专为临床目的而设计的MiCBT的四阶段系统方法，包括个人内（阶段1）暴露（阶段2），人际（阶段3）和共情（阶段4）技能组，是其他正念中的一个显着特征-基于基础的干预措施（MBI）。这项研究的目的是调查MiCBT组是否以及如何减轻患有一系列常见精神疾病的患者的抑郁和焦虑症状。方法通过医生转诊招募的参与者（n = 120）将被随机分配到MiCBT或候补名单对照中。纳入标准为18-75岁；英语流利，凯斯勒心理困扰量表（K10）得分为20或更高。MiCBT治疗组接受了为期8周的MiCBT干预，该干预是通过私人心理学实践进行的。参与者完成一套在线自我报告措施，并记录每周进行的冥想练习量。对照组接受常规治疗并在同一时间点完成措施。主要结局指标为抑郁焦虑压力量表21（DASS-21）和K10。分析将使用混合模型重复测量。讨论MiCBT提供适用于各诊断组的综合治疗系统的潜在能力将使其成为可用MBI的诱人补充。试验注册本试验已在澳大利亚和新西兰临床试验注册中心注册：ACTRN12617000061336；注册日期：2017年1月11日。