Cardiolipins (CL) are a special lipid class which plays a main role in energy metabolism in mitochondria and is involved in apoptosis. In contrast to other glycerophospholipids, they contain four fatty acyl residues which results in a high structural diversity. Oxidation, for example by reactive oxygen species, or lyso forms such as monolyso‐CL (MLCL), increases this diversity. Mass spectrometric analysis and computational identification of CL, MLCL and their oxidation products is therefore a challenging task.

中文翻译：

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液相色谱/高分辨率质谱和亲水相互作用液相色谱制备样品后，通过液相色谱/高分辨率质谱和Kendrick质量缺陷图分析人工氧化的心磷脂和单溶心磷脂

心磷脂（CL）是一种特殊的脂质类，在线粒体的能量代谢中起主要作用，并参与细胞凋亡。与其他甘油磷脂相反，它们包含四个脂肪酰基残基，从而导致高度的结构多样性。氧化，例如被活性氧或溶血形式的氧化，如单溶酶-CL（MLCL），增加了这种多样性。因此，CL，MLCL及其氧化产物的质谱分析和计算鉴定是一项艰巨的任务。