Polymer-based wafers containing gold nanoparticles (AuNP) were prepared using κ-carrageenan (κC), locust bean gum (LBG) and polyvinyl alcohol (PVA) at ratios of 42/22/13% ^w/_w and 35/15/17% ^w/_w. The synthesized AuNPs were evaluated for their particle size and morphology. The produced wafers containing AuNPs were investigated for their physicochemical, morphological, mechanical, and swelling properties. In addition, bacterial barrier activity and in vitro cytotoxicity were also evaluated in this study. The AuNPs obtained were spherical in shape (~ 10–15 nm in diameter) and exhibited a single bell-shaped UV–vis absorption band centered ~ 540 nm. FT–IR spectra of the wafers containing AuNPs exhibited a shift of ν(O=S=O) absorption band toward a lower wavenumber and a shift of ν(OH) absorption band toward a higher wavenumber due to the coordination of OH groups to AuNPs and their interaction with O=S=O groups of κC, respectively. SEM images confirmed the porous structure of the produced wafers, being the surface area, mechanical properties, and swelling behavior directly affected by changing both the initial amount of [Au⁺³] and the composition of the wafers. Lastly, the produced wafers showed non-toxicity to NIH–3T3 fibroblast cells, and they also serve as a bacterial barrier. These findings endorsed the claim that the produced wafers containing AuNPs could be a promising material for wound dressing applications.

使用κ-角叉菜胶（κC），刺槐豆胶（LBG）和聚乙烯醇（PVA）制备比例为42/22/13％^w / _w和35/15/17的含金纳米颗粒（AuNP）的聚合物基晶圆％^w / _w。评估了合成的AuNPs的粒径和形态。对包含AuNPs的晶圆进行了物理化学，形态，机械和溶胀性能的研究。此外，在这项研究中还评估了细菌屏障活性和体外细胞毒性。获得的AuNP呈球形（直径约10-15 nm），并呈现出一个单一的钟形UV-vis吸收带，中心为540 nm。含有AuNPs的晶片的FT-IR光谱显示出ν（O = S = O）吸收带向较低波数移动，而ν（O H）吸收带向较高波数移动，这归因于O H基团与AuNPs的配位及其与ONP的O = S = O基团的相互作用κC。SEM图像证实了所生产的晶片的多孔结构，其表面积，机械性能和溶胀行为直接受到改变[Au ⁺³ ]的初始量和晶片组成的影响。最后，所生产的威化饼对NIH-3T3成纤维细胞没有毒性，并且还可以作为细菌屏障。这些发现支持了这样的说法，即所生产的包含AuNPs的晶圆可能是用于伤口包扎应用的有前途的材料。