Sarcoidosis has been a disease of puzzling occurrence and clinical course. Multiple immunological markers have been noted to be altered within sarcoidosis, however there is variable consistency among these reports. Previous studies have shown sarcoidosis to be a primary T cell-mediated disease, yet new data concerning B cell and mycobacterial involvement have been brought to light. The possibility of a uniform biomarker to characterize sarcoidosis presence, severity and prognosis greatly increases the movement towards directed and specialized treatment for this rare disease.

中文翻译：

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免疫反应生物标志物可作为结节病的存在，预后和可能的治疗方法的指标：免疫病原学的观点。

结节病一直是令人费解的疾病和临床过程的疾病。结节病中多种免疫学标记已被改变，但是这些报告之间存在不一致的一致性。先前的研究表明结节病是原发性T细胞介导的疾病，但有关B细胞和分枝杆菌受累的新数据却被发现。统一的生物标记物可以表征结节病的存在，严重性和预后，大大增加了针对这种罕见疾病的定向和专门治疗的趋势。