Negative regulation of gene expression by transcriptional silencers has been difficult to study due to limited defined examples. A new study by Gisselbrecht et al. has dramatically increased the number of identified silencers and reveals that they are bifunctional regulatory sequences that also act as gene expression-promoting enhancers.

中文翻译：

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沉默子，增强子和多功能调控基因组。

由于限定的例子有限，难以研究转录沉默子对基因表达的负调控。Gisselbrecht等人的一项新研究。已显着增加了已鉴定的沉默子的数量，并揭示了它们是双功能调节序列，也可作为促进基因表达的增强子。