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Casein Kinase 1δ Triggers Giant Ankyrin Expression.
Developmental Cell ( IF 10.7 ) Pub Date : 2020-01-06 , DOI: 10.1016/j.devcel.2019.12.012
Katherine L Thompson-Peer 1
Affiliation  

During development, neurons form growth cones and neurites, but later reduce these activities to maintain a stable architecture. In this issue of Developmental Cell, LaBella et al. demonstrate that CK1δ plays a key role in winding down developmental processes exclusively by regulating poly(A) site choice to promote giant Ankyrin isoform expression.

中文翻译:

酪蛋白激酶1δ触发巨锚蛋白表达。

在发育过程中,神经元形成生长锥和神经突,但后来减少了这些活动以维持稳定的结构。在本期《发育细胞》中,LaBella等人。证明CK1δ通过调节poly(A)位点选择以促进巨锚蛋白同工型表达,在终止发育过程中起关键作用。
更新日期:2020-01-06
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