BACKGROUND Hypertension is the most common medical problem encountered in pregnancy and is a leading cause of perinatal and maternal morbidity and mortality. However, its magnitude and risk factors yet not adequately assessed at the study area. METHODS Facility-based retrospective unmatched case-control study was conducted to identify risk factors associated with Hypertensive disorders of pregnancy in Nekemte Referral Hospital just two years back from study period July 1, 2015, to June 30, 2017. Bivariate logistic regression was considered for inclusion in to the multivariate logistic regression. Finally, multi varaite analysis were done to identify risk factors of hypertensive disorders of pregnancy. RESULTS Among 6826 total delivery records from July 2015 -June 2017, 199 women developed hypertension during pregnancy. Among 199 women 153(76.9%) were pre-eclampsia/eclampsia,28(14.1%) were gestational hypertension, 14(0.7%) were superimposed hypertension and 4 (2.9%) were chronic hypertension. Age ≥ 35 (AOR: 2.51, 95% CI: 1.08, 5.83), rural residential area (AOR: 1.79, 95% CI: 1.150, 2.799), prim gravida (AOR: 3.39, 95% CI: 2.16, 5.33), null parity (AOR: 4.35, 95% CI: 2.36, 8.03), positive history of abortion (AOR: 4.39, 95% CI: 1.64, 11.76), twin pregnancy (AOR: 3.78, 95% CI: 1.52, 9.39), lack of ANC follow up (AOR: 3.05, 95% CI: 1.56, 5.96) as well as positive pre-existing hypertension (AOR: 3.81, 95% CI: 1.69, 8.58), positive family history of hypertension (AOR: 5.04, 95% CI: 2.66, 9.56) and positive history of diabetes mellitus (AOR: 5.03, 95% CI: 1.59, 15.89) were risk factors for hypertensive disorders during pregnancy. CONCLUSION This study found that Women with hypertension during pregnancy have a greater risk of developing adverse pregnancy outcome as compared to normotensive pregnant women. so, identification of these risk factors would be useful for early diagnosis of hypertension disorders during pregnancy to give appropriate clinical monitoring and treatments and timely managing maternal and perinatal complications.

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2015 年 7 月至 2017 年 6 月，埃塞俄比亚 Nekemte 转诊医院与妊娠期高血压疾病相关的危险因素：病例对照研究。

背景技术高血压是妊娠期最常见的医学问题，并且是围产期和孕产妇发病和死亡的主要原因。然而，其规模和风险因素尚未在研究区域得到充分评估。方法 在 Nekemte 转诊医院进行了基于设施的回顾性非匹配病例对照研究，以确定与妊娠期高血压疾病相关的危险因素，研究期为两年前，即 2015 年 7 月 1 日至 2017 年 6 月 30 日。纳入多元逻辑回归。最后，进行多变量分析以确定妊娠期高血压疾病的危险因素。结果 2015年7月至2017年6月共6826份分娩记录中，199名妇女在妊娠期间出现高血压。199名女性中，子痫前期/子痫153例（76.9%），妊娠期高血压28例（14.1%），叠加高血压14例（0.7%），慢性高血压4例（2.9%）。年龄≥35岁（AOR：2.51，95％CI：1.08，5.83），农村居民区（AOR：1.79，95％CI：1.150，2.799），初孕（AOR：3.39，95％CI：2.16，5.33），无效胎次（AOR：4.35，95% CI：2.36，8.03），阳性流产史（AOR：4.39，95% CI：1.64，11.76），双胎妊娠（AOR：3.78，95% CI：1.52，9.39），缺乏 ANC 随访（AOR：3.05，95% CI：1.56，5.96）以及阳性既往高血压（AOR：3.81，95% CI：1.69，8.58），阳性高血压家族史（AOR：5.04， 95% CI: 2.66, 9.56) 和糖尿病阳性病史 (AOR: 5.03, 95% CI: 1.59, 15.89) 是妊娠期高血压疾病的危险因素。结论 这项研究发现，与血压正常的孕妇相比，妊娠期间患有高血压的女性发生不良妊娠结局的风险更大。因此，识别这些危险因素将有助于早期诊断妊娠期高血压疾病，以便给予适当的临床监测和治疗，并及时管理孕产妇和围产期并发症。