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Single-cell ATP detection and content analyses in electrostimulus-induced apoptosis using functionalized glass nanopipettes.
Chemical Communications ( IF 4.3 ) Pub Date : 2020-01-13 , DOI: 10.1039/c9cc08889j
Dandan Wang 1 , Guohua Qi 2 , Ya Zhou 1 , Ying Zhang 1 , Bo Wang 3 , Ping Hu 1 , Yongdong Jin 4
Affiliation  

A glass nanopipette functionalized with ATP-responsive gold nanoparticle assemblies was developed for ATP detection in single-cells and used for analysing the content change of ATP during electrostimulus (ES)-induced apoptosis. The variation of ATP content in single normal cells and cancer cells during apoptosis was detected by the method.

中文翻译:

使用功能化的玻璃纳米移液器在电刺激诱导的凋亡中进行单细胞ATP检测和含量分析。

开发了具有ATP响应金纳米粒子组件功能化的玻璃纳米移液管,用于单细胞中的ATP检测,并用于分析电刺激(ES)诱导的细胞凋亡过程中ATP的含量变化。该方法检测了单个正常细胞和癌细胞凋亡过程中ATP含量的变化。
更新日期:2020-01-13
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