PURPOSE Cases of chemotherapy-induced peripheral neuropathy (CIPN) under-reporting have been sporadically described in the literature, but no studies have focused on actively examining this behavior. Our primary aim was to identify women who purposefully under-reported CIPN, along with reasons for doing so. A secondary aim was to explore factors enabling or hindering communication of CIPN to clinicians. METHODS Semi-structured interviews were conducted with women with breast cancer who had received paclitaxel in a prospective observational study. The interview guide was developed based on factors hypothesized to influence side effect disclosure to clinicians. Interviews were recorded, transcribed verbatim, and thematically content analyzed. RESULTS Thirty-four women were interviewed. Three main themes emerged from the analysis: (1) enablers of CIPN reporting (e.g., positive relationship with the oncology team, sufficient appointment time, existence of alternative communication channels to office visits, expectation of CIPN as a side effect); (2) deterrents to CIPN reporting (e.g., perception of need to complete the full course of therapy, fear of treatment discontinuation, lack of knowledge of long-term consequences of CIPN); and (3) balancing survival versus functional impairment due to CIPN. Women prioritized efficacy over CIPN until physical functioning was meaningfully affected. No patients reported purposeful CIPN under-reporting, but three women admitted having considered doing so. CONCLUSIONS Despite the lack of evidence of CIPN withholding, women considered both the effectiveness and the toxicity of paclitaxel treatment, as well as beliefs about treatment and long-term consequences of CIPN and relationship with the oncology team, when deciding whether to report CIPN symptoms.

中文翻译：

---

向乳腺癌妇女的临床医生报告紫杉醇诱发的周围神经病变症状：一项定性研究。

目的在文献中偶尔描述了化疗引起的周围神经病变（CIPN）报道不足的病例，但尚无研究集中于积极研究这种行为。我们的主要目的是确定故意漏报CIPN的妇女以及这样做的原因。第二个目的是探讨促成或阻碍CIPN与临床医生沟通的因素。方法对前瞻性观察研究中接受紫杉醇的乳腺癌妇女进行半结构式访谈。访谈指南是基于被认为会影响向临床医生披露副作用的因素而制定的。记录访谈，逐字记录并分析主题内容。结果采访了34名女性。分析得出了三个主要主题：（1）CIPN报告的促成因素（例如，与肿瘤学团队的积极关系，足够的任命时间，办公室访问存在替代沟通渠道，期望CIPN产生副作用）；（2）阻止CIPN报告（例如，认为需要完成整个治疗过程，担心终止治疗，不了解CIPN的长期后果）；（3）在生存与因CIPN引起的功能障碍之间取得平衡。在身体功能受到重大影响之前，女性优先于CIPN进行疗效。没有患者报告有目的的CIPN漏报，但三名女性承认考虑这样做。结论尽管没有CIPN扣留的证据，但女性同时考虑了紫杉醇治疗的有效性和毒性，