There are very few reports about complete-blood-count (CBC) findings in paediatric tuberculosis. We assessed the prevalence and predictors of haematologic abnormalities and the utility of a routine CBC in initial management of paediatric TB. We reviewed records and results of investigations of all children and adolescents (ages 0–18) treated for TB disease at the Hospital for Sick Children, Toronto, Canada from January 2002 to December 2012. Anaemia was found in 52/138 (42%) patients, was often microcytic, more prevalent in adolescent females (Odds Ratio (OR) 3.7 [95% confidence intervals (CI) 1.27–10.6]) and those with disseminated disease (OR 3.60 [95% CI 1.12–11.53]), and often resolved with anti-tuberculous treatment. Only 4 children received iron therapy. White cell abnormalities that occurred often suggested diagnoses other than TB: lymphopenia occurred in 30/124 patients (24%) (all HIV negative) and neutrophilia in 20/124 (16%) patients, 9 of whom had pulmonary airspace disease. An initial routine CBC seldom changed patient management and had limited utility.

中文翻译：

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结核儿童和青少年的全血细胞计数：贫血，淋巴细胞减少症和中性粒细胞增多症的实用性和患病率

关于小儿结核病的全血细胞计数（CBC）发现的报道很少。我们评估了血液学异常的发生率和预测因素，以及常规CBC在小儿结核病初始治疗中的效用。我们回顾了2002年1月至2012年12月在加拿大多伦多的儿童病医院接受结核病治疗的所有儿童和青少年（0至18岁）的记录和调查结果。在52/138（42％）的人群中发现了贫血患者，通常是小细胞性的，在青春期女性中更为普遍（几率（OR）3.7 [95％置信区间（CI）1.27-10.6]）和那些患有弥漫性疾病的患者（OR 3.60 [95％CI 1.12-11.53]），以及常通过抗结核治疗解决。只有4名儿童接受了铁疗法。发生的白细胞异常通常建议诊断为结核以外的其他疾病：淋巴细胞减少症发生在30/124位患者中（24％）（全部为HIV阴性），中性粒细胞增多症发生在20/124位患者（16％）中，其中9位患有肺空洞症。最初的常规CBC很少改变患者的治疗方式，并且效用有限。