PURPOSE Given increasing interest in using the capability approach for health economic evaluations and a growing literature, this paper aims to synthesise current information about the characteristics of capability instruments and their application in health economic evaluations. METHODS A systematic literature review was conducted to assess studies that contained information on the development, psychometric properties and valuation of capability instruments, or their application in economic evaluations. RESULTS The review identified 98 studies and 14 instruments for inclusion. There is some evidence on the psychometric properties of most instruments. Most papers found moderate-to-high correlation between health and capability measures, ranging between 0.41 and 0.64. ASCOT, ICECAP-A, -O and -SCM instruments have published valuation sets, most frequently developed using best-worst scaling. Thirteen instruments were originally developed in English and one in Portuguese; however, some translations to other languages are available. Ten economic evaluations using capability instruments were identified. The presentation of results show a lack of consensus regarding the most appropriate way to use capability instruments in economic evaluations with discussion about capability-adjusted life years (CALYs), years of capability equivalence and the trade-off between maximisation of capability versus sufficient capability. CONCLUSION There has been increasing interest in applying the capability-based approach in health economic evaluations, but methodological and conceptual issues remain. There is still a need for direct comparison of the different capability instruments and for clear guidance on when and how they should be used in economic evaluations.

中文翻译：

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健康相关干预措施经济评估中的能力工具：文献比较综述。


目的鉴于人们对使用能力方法进行卫生经济评估的兴趣日益浓厚，并且文献不断增多，本文旨在综合有关能力工具的特征及其在卫生经济评估中的应用的当前信息。方法 我们进行了系统的文献综述，以评估包含有关能力工具的发展、心理测量特性和评估或其在经济评估中的应用的信息的研究。结果 审查确定了 98 项研究和 14 种仪器可供纳入。大多数仪器的心理测量特性都有一些证据。大多数论文发现健康和能力测量之间存在中度到高度的相关性，范围在 0.41 到 0.64 之间。 ASCOT、ICECAP-A、-O 和 -SCM 工具已发布估值集，最常使用最佳-最差缩放来开发。十三种乐器最初是用英语开发的，一种是用葡萄牙语开发的；但是，可以提供一些其他语言的翻译。确定了使用能力工具的十项经济评估。结果的呈现表明，对于在经济评估中使用能力工具的最合适方式缺乏共识，并讨论了能力调整生命年（CALY）、能力等效年数以及能力最大化与充足能力之间的权衡。结论 人们对在卫生经济评估中应用基于能力的方法越来越感兴趣，但方法和概念问题仍然存在。仍然需要对不同的能力工具进行直接比较，并就何时以及如何在经济评估中使用它们提供明确的指导。