OBJECTIVE To estimate the impact of nonsurgical periodontal treatment (NSPT) on patients' oral health-related quality of life (OHRQoL). The focused question for this systematic review was: in adults patients with periodontitis, does NSPT improve oral health-related quality of life? MATERIAL AND METHODS Five databases (PubMed, CIHNL, EMBASE, LILACS and CENTRAL) were searched up to April 2019 (PROSPERO CRD42018103393). Intervention trials and cohort studies assessing the OHRQoL data of adults with periodontitis, enduring non-surgical periodontal treatment (NSPT) were eligible for inclusion. Subgroup random-effects meta-analysis was conducted methodically. RESULTS Overall, 491 studies were retrieved, out of which 19 met the inclusion criteria. Two randomized clinical trials (RCTs) and ten cohort studies were further analysed. Seven cohort studies were included in the statistical analysis. Subgroup meta-analyses of cohort studies revealed that NSPT improves in average 2.49 (95% CI 0.95-4.02), 8.94 (95% CI 6.89-10.99) and 6.49 (95% CI 5.11-7.88) OHRQoL levels at 1-2 weeks, 3-4 weeks and 6-12 weeks of post-treatment, respectively. CONCLUSIONS NSPT procedures greatly improve the oral health-related quality of life within a short time, remaining stable after 3 months of treatment. CLINICAL RELEVANCE This systematic review brings forward summary evidence that NSPT improves the OHRQoL in adults with periodontitis from a patient-centred perception and remain stable in the short term.

中文翻译：

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非手术性牙周治疗对口腔健康相关生活质量的影响：系统评价和荟萃分析。

目的评估非手术牙周治疗（NSPT）对患者口腔健康相关生活质量（OHRQoL）的影响。该系统评价的重点问题是：在成人牙周炎患者中，NSPT是否能改善与口腔健康相关的生活质量？材料和方法检索了截至2019年4月的五个数据库（PubMed，CIHNL，EMBASE，LILACS和CENTRAL）（PROSPERO CRD42018103393）。评估经牙周炎治疗且经非手术治疗的成人牙周炎的OHRQoL数据的干预试验和队列研究均符合纳入条件。有系统地进行亚组随机效应荟萃分析。结果总体上，检索到491项研究，其中19项符合纳入标准。进一步分析了两项随机临床试验（RCT）和十项队列研究。统计分析中包括七项队列研究。队列研究的亚组荟萃分析显示，NSPT在1-2周时的OHRQoL水平平均提高了2.49（95％CI 0.95-4.02），8.94（95％CI 6.89-10.99）和6.49（95％CI 5.11-7.88），治疗后3-4周和6-12周。结论NSPT程序可在短时间内极大地改善与口腔健康相关的生活质量，治疗3个月后保持稳定。临床相关性这项系统的综述提出了一些总结性证据，表明NSPT可以以患者为中心，改善成人牙周炎的OHRQoL，并在短期内保持稳定。（11-7.88）治疗后1-2周，3-4周和6-12周的OHRQoL水平。结论NSPT程序可在短时间内极大地改善与口腔健康相关的生活质量，治疗3个月后保持稳定。临床相关性这项系统的综述提出了一些总结性证据，表明NSPT可以以患者为中心，改善成人牙周炎的OHRQoL，并在短期内保持稳定。（11-7.88）治疗后1-2周，3-4周和6-12周的OHRQoL水平。结论NSPT程序可在短时间内极大地改善与口腔健康相关的生活质量，治疗3个月后保持稳定。临床相关性这项系统的综述提出了一些总结性证据，表明NSPT可以以患者为中心，改善成人牙周炎的OHRQoL，并在短期内保持稳定。