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Complete genome sequencing and genetic analysis of a Japanese porcine torovirus strain detected in swine feces.
Archives of Virology ( IF 2.5 ) Pub Date : 2019-12-20 , DOI: 10.1007/s00705-019-04514-4
Yuki Fujii 1 , Yuki Kashima 1 , Fujiko Sunaga 2 , Hiroshi Aoki 3 , Ryo Imai 4 , Kaori Sano 5 , Yukie Katayama 4 , Tsutomu Omatsu 4 , Mami Oba 4 , Tetsuya Furuya 6 , Satoko Tsuzuku 1 , Yoshinao Ouchi 1 , Junsuke Shirai 6 , Tetsuya Mizutani 4 , Tomoichiro Oka 7 , Makoto Nagai 2, 4
Affiliation  

We sequenced the complete genome of a porcine torovirus (PToV) strain from Japan for the first time. Whole-genome analysis revealed that this strain (Iba/2018) has a mosaic sequence composed of at least three genome backgrounds, related to US, Chinese and German PToV strains. Clear recombination breakpoints were detected in the M and HE coding regions. A similarity plot and structural analysis demonstrated that the HE coding region exhibits the highest diversity, and the most sequence variation was found in the lectin domain. PToVs were divided into two lineages in the HE region, whereas clear lineages were not found in other regions.
更新日期:2020-01-04
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