Bovine herpesvirus types 1 (BoHV-1) and 5 (BoHV-5) are two closely related alphaherpesviruses. BoHV-1 causes several syndromes in cattle, including respiratory disease and sporadic cases of encephalitis, whereas BoHV-5 is responsible for meningoencephalitis in calves. Although both viruses are neurotropic, they differ in their neuropathogenic potential. This review summarizes the findings on the specific mechanisms and pathways known to modulate the pathogenesis of BoHV-1 and BoHV-5, particularly in relation to respiratory and neurological syndromes, which characterize BoHV-1 and BoHV-5 infections, respectively.

中文翻译：

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牛1型和5型牛疱疹病毒的显着特征以及可能影响临床结果的病毒-宿主相互作用。

牛疱疹病毒类型1（BoHV-1）和5（BoHV-5）是两种密切相关的甲疱疹病毒。BoHV-1引起牛的几种综合征，包括呼吸系统疾病和偶发性脑炎，而BoHV-5则引起小牛脑膜脑炎。尽管两种病毒都是嗜神经的，但它们的神经致病潜能却有所不同。这篇综述总结了已知的特定机制和途径的发现，这些机制和途径已知可调节BoHV-1和BoHV-5的发病机理，特别是与分别以BoHV-1和BoHV-5感染为特征的呼吸综合征和神经综合征有关。