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Epigenetics in age-related macular degeneration: new discoveries and future perspectives.
Cellular and Molecular Life Sciences ( IF 6.2 ) Pub Date : 2020-01-02 , DOI: 10.1007/s00018-019-03421-w
M Gemenetzi 1 , A J Lotery 2
Affiliation  

The study of epigenetics has explained some of the 'missing heritability' of age-related macular degeneration (AMD). The epigenome also provides a substantial contribution to the organisation of the functional retina. There is emerging evidence of specific epigenetic mechanisms associated with AMD. This 'AMD epigenome' may offer the chance to develop novel AMD treatments.

中文翻译:


年龄相关性黄斑变性的表观遗传学:新发现和未来前景。



表观遗传学研究解释了年龄相关性黄斑变性(AMD)的一些“遗传性缺失”。表观基因组还对功能性视网膜的组织做出了重大贡献。有新的证据表明与 AMD 相关的特定表观遗传机制。这种“AMD 表观基因组”可能为开发新型 AMD 治疗方法提供机会。
更新日期:2020-01-04
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