The present study assessed the effects of β-glucooligosaccharides (β-GOS) derived from barley β-glucan on the proliferation and antimicrobial activity of probiotics. All cocci examined in this study and several species of Lactobacilli and bifidobacteria were able to utilize β-GOS as a sole carbon source. In addition, the absence of significant growth of certain pathogens on β-GOS compared to prebiotics fructo-oligosaccharide (FOS) and inulin substrates demonstrates the probiotic specificity of β-GOS metabolism. Increased anti-microbial activities were observed in Lactococcus lactis subsp. lactis, Lactobacillus reuteri, and Pediococcus acidilactici grown in media with β-GOS as the sole carbon source over glucose. β-GOS enabled sustained L. lactis subsp. lactis growth in the exponential phase, resulting in an approximately 25% increase in nisin Z production compared with glucose. These results suggest that β-GOS can selectively modulate probiotic growth in particular cocci, and antimicrobial activity, with important implications for future research in nutrition as well as industrial applications.

本研究评估了大麦β-葡聚糖衍生的β-葡萄糖寡糖（β-GOS）对益生菌增殖和抗菌活性的影响。在这项研究中检查的所有球菌以及几种乳酸杆菌和双歧杆菌都能够利用β-GOS作为唯一碳源。另外，与益生元低聚果糖（FOS）和菊粉底物相比，β-GOS上某些病原体没有明显生长，这证明了β-GOS代谢的益生菌特异性。在乳酸乳球菌亚种中观察到增加的抗微生物活性。球菌，罗伊氏乳杆菌和乳酸片球菌在以β-GOS作为葡萄糖的唯一碳源的培养基中生长。β-GOS使L持续存在。乳酸亚种 乳酸在指数期生长，与葡萄糖相比，乳链菌肽Z产量增加了约25％。这些结果表明，β-GOS可以选择性调节益生菌的生长，尤其是球菌和抗菌活性，这对营养和工业应用的未来研究具有重要意义。