Journal of Biological Dynamics ( IF 1.8 ) Pub Date : 2019-01-08 , DOI: 10.1080/17513758.2018.1562572 Chunqing Wu 1 , Patricia J Y Wong 2
In this paper, we establish a mathematical model with two delays to reflect the intrinsic and extrinsic incubation periods of virus in dengue transmission. The basic reproduction number of the model is defined. It is proved that the disease-free equilibrium is stable when and the positive equilibrium is stable when . Next, we derive an estimation formula for the reproduction number when the human population is partially susceptible to dengue. As an application, the values of dengue transmission in Singapore in the years 2013–2015 are estimated. Our estimation method can be applied to estimating of other infectious diseases, especially when the human population is not completely susceptible to the disease.
中文翻译:
登革热传播:具有离散时间延迟并估计繁殖次数的数学模型。
在本文中,我们建立了具有两个延迟的数学模型,以反映登革热传播中病毒的内在和外在潜伏期。基本复制数模型的定义。证明了在以下情况下无病平衡是稳定的 当以下情况时,正平衡是稳定的 。接下来,我们得出再现次数的估计公式当人口部分易患登革热时。作为应用,估计了2013-2015年新加坡的登革热传播值。我们的估计方法可以应用于估计其他传染病,尤其是当人口不完全易感时。